The computational restoration of autoradiographic images.

A double integral formula is derived for the distortion in an autoradiographic image due to electron "cross-fire", and a deconvolution procedure for image restoration using a fast Fourier transform algorithm is developed. The technique is applied to a simulated autoradiograph of a uniform disc source and is found to give excellent results. Further image enhancement is obtained from the use of a spatially moving average smoothing process.