Literature DB >> 820549

Epilepsy, a product of trauma in our time.

W F Caveness.   

Abstract

Using data obtained by the National Center for Health Statistics through household interviews, an estimate of 8,100,000 cases of head injury was determined for the civilian population of the United States in 1974. Excluding contusions and lacerations of the scalp, face, and neck; there remained 1,900,000 with concussion, skull fractures, intracranial hemorrhage, cerebral laceration, or other intracranial injury. Extrapolating from the military experience with craniocerebral trauma admittedly a rough approximation, it is estimated that in 30% of this latter group one more seizures will develop. Both severity of the injury and the predisposition of the injured are thought to play a part in the occurrence of seizures, with the predisposition playing the dominant role in the persistence of seizures. The following gradation of posttraumatic epilepsy is predicted for the 1,900,000 with the greater implication of brain damage: 1,340,000 will never have a seizure; 560,000 will develop one or more attacks, most of which will begin in 1974, 1975, or 1976. In 280,000 of these, the attacks will be transient and of little consequence. In an equal number, the attacks will require medical attention, and in some 140,000 the seizures will be intractable to therapy. This latter group represents 7% of the 1,900,000 cases. Attention is directed to the practical problems in the control of carniocerebral trauma and of posttraumatic epilepsy.

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Year:  1976        PMID: 820549     DOI: 10.1111/j.1528-1157.1976.tb03398.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN: 0013-9580            Impact factor:   5.864


  13 in total

1.  Road safety: BMA comments.

Authors:  D F Scott
Journal:  Br Med J       Date:  1976-12-25

2.  Post-traumatic epilepsy.

Authors: 
Journal:  Br Med J       Date:  1978-07-22

Review 3.  Pharmacological prophylaxis of post-traumatic epilepsy.

Authors:  A Iudice; L Murri
Journal:  Drugs       Date:  2000-05       Impact factor: 9.546

4.  Protection from glutamate-induced excitotoxicity by memantine.

Authors:  Melinda K Kutzing; Vincent Luo; Bonnie L Firestein
Journal:  Ann Biomed Eng       Date:  2011-12-28       Impact factor: 3.934

5.  Impact of injury location and severity on posttraumatic epilepsy in the rat: role of frontal neocortex.

Authors:  Giulia Curia; Michael Levitt; Jason S Fender; John W Miller; Jeffrey Ojemann; Raimondo D'Ambrosio
Journal:  Cereb Cortex       Date:  2010-11-26       Impact factor: 5.357

6.  Increased Expression of Epileptiform Spike/Wave Discharges One Year after Mild, Moderate, or Severe Fluid Percussion Brain Injury in Rats.

Authors:  Thomas Sick; Joseph Wasserman; Amade Bregy; Justin Sick; W Dalton Dietrich; Helen M Bramlett
Journal:  J Neurotrauma       Date:  2017-06-14       Impact factor: 5.269

7.  Magnetization transfer MR imaging in patients with posttraumatic epilepsy.

Authors:  Rajesh Kumar; Rakesh K Gupta; Mazhar Husain; Davender K Vatsal; Sanjeev Chawla; Ram Kishore S Rathore; Sunil Pradhan
Journal:  AJNR Am J Neuroradiol       Date:  2003-02       Impact factor: 3.825

Review 8.  Posttraumatic epilepsy: hemorrhage, free radicals and the molecular regulation of glutamate.

Authors:  L J Willmore; Yuto Ueda
Journal:  Neurochem Res       Date:  2008-09-11       Impact factor: 3.996

9.  Epilepsy in chronic subdural haematoma.

Authors:  Z Kotwica; J Brzeiński
Journal:  Acta Neurochir (Wien)       Date:  1991       Impact factor: 2.216

10.  Structural abnormalities in patients with insular/peri-insular epilepsy: spectrum, frequency, and pharmacoresistance.

Authors:  M-C Chevrier; C Bard; F Guilbert; D K Nguyen
Journal:  AJNR Am J Neuroradiol       Date:  2013-06-27       Impact factor: 3.825

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