Literature DB >> 8204656

Expression of Na+-independent isoleucine transport activity from rat brain in Xenopus laevis oocytes.

S Bröer1, A Bröer, B Hamprecht.   

Abstract

Poly(A)+ RNA from C6-BU-1 rat glioma cells and rat astroglial cells induced isoleucine transport activity when injected into Xenopus laevis oocytes. The Na+-independent component of isoleucine transport was inhibited by leucine, phenylalanine and 2-aminobicyclo[2,2,1]heptane-2-carboxylic acid (BCH) but neither by methylaminoisobutyric acid (MeAIB) nor lysine. A Km value of approx. 100 microM was determined for the Na+-independent transport of isoleucine. These data are in accordance with expression of a system L like transporter. By injection of size fractionated poly(A)+ RNA a length of approx. 1.9 kb was determined for the pertinent mRNA.

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Year:  1994        PMID： 8204656     DOI： 10.1016/0005-2736(94)90147-3

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  18 in total

1.  Neutral amino acid transporter ASCT2 displays substrate-induced Na+ exchange and a substrate-gated anion conductance.

Authors:  A Bröer; C Wagner; F Lang; S Bröer
Journal:  Biochem J       Date:  2000-03-15       Impact factor: 3.857

2.  Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy.

Authors:  F Lang; K Klingel; C A Wagner; C Stegen; S Warntges; B Friedrich; M Lanzendorfer; J Melzig; I Moschen; S Steuer; S Waldegger; M Sauter; M Paulmichl; V Gerke; T Risler; G Gamba; G Capasso; R Kandolf; S C Hebert; S G Massry; S Broër
Journal:  Proc Natl Acad Sci U S A       Date:  2000-07-05       Impact factor: 11.205

3.  Upregulation of the Na⁺-coupled phosphate cotransporters NaPi-IIa and NaPi-IIb by B-RAF.

Authors:  Tatsiana Pakladok; Zohreh Hosseinzadeh; Aleksandra Lebedeva; Ioana Alesutan; Florian Lang
Journal:  J Membr Biol       Date:  2013-11-21       Impact factor: 1.843

4.  Discrimination of two amino acid transport activities in 4F2 heavy chain- expressing Xenopus laevis oocytes.

Authors:  A Bröer; B Hamprecht; S Bröer
Journal:  Biochem J       Date:  1998-08-01       Impact factor: 3.857

5.  Expression of the surface antigen 4F2hc affects system-L-like neutral-amino-acid-transport activity in mammalian cells.

Authors:  S Bröer; A Bröer; B Hamprecht
Journal:  Biochem J       Date:  1997-06-01       Impact factor: 3.857

6.  Upregulation of KCNQ1/KCNE1 K+ channels by Klotho.

Authors:  Ahmad Almilaji; Tatsiana Pakladok; Carlos Muñoz; Bernat Elvira; Mentor Sopjani; Florian Lang
Journal:  Channels (Austin)       Date:  2014       Impact factor: 2.581

7.  The heterodimeric amino acid transporter 4F2hc/LAT1 is associated in Xenopus oocytes with a non-selective cation channel that is regulated by the serine/threonine kinase sgk-1.

Authors:  C A Wagner; A Bröer; A Albers; N Gamper; F Lang; S Bröer
Journal:  J Physiol       Date:  2000-07-01       Impact factor: 5.182

Review 8.  Interactions in the Metabolism of Glutamate and the Branched-Chain Amino Acids and Ketoacids in the CNS.

Authors:  Marc Yudkoff
Journal:  Neurochem Res       Date:  2016-10-01       Impact factor: 3.996

9.  Expression of a renal type I sodium/phosphate transporter (NaPi-1) induces a conductance in Xenopus oocytes permeable for organic and inorganic anions.

Authors:  A E Busch; A Schuster; S Waldegger; C A Wagner; G Zempel; S Broer; J Biber; H Murer; F Lang
Journal:  Proc Natl Acad Sci U S A       Date:  1996-05-28       Impact factor: 11.205

10.  Cystinuria-specific rBAT(R365W) mutation reveals two translocation pathways in the amino acid transporter rBAT-b0,+AT.

Authors:  Marta Pineda; Carsten A Wagner; Angelika Bröer; Paul A Stehberger; Simone Kaltenbach; Josep Ll Gelpí; Rafael Martín Del Río; Antonio Zorzano; Manuel Palacín; Florian Lang; Stefan Bröer
Journal:  Biochem J       Date:  2004-02-01       Impact factor: 3.857
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