Literature DB >> 8201587

3-[4-(1,2-Diphenylbut-1-enyl)phenyl]acrylic acid: a non-steroidal estrogen with functional selectivity for bone over uterus in rats.

T M Willson1, B R Henke, T M Momtahen, P S Charifson, K W Batchelor, D B Lubahn, L B Moore, B B Oliver, H R Sauls, J A Triantafillou.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 8201587     DOI： 10.1021/jm00037a002

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


× No keyword cloud information.
  19 in total

1.  Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs).

Authors:  Karen J Kieser; Dong Wook Kim; Kathryn E Carlson; Benita S Katzenellenbogen; John A Katzenellenbogen
Journal:  J Med Chem       Date:  2010-04-22       Impact factor: 7.446

2.  Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain.

Authors:  Abhishek Sharma; Weiyi Toy; Valeria Sanabria Guillen; Naina Sharma; Jian Min; Kathryn E Carlson; Christopher G Mayne; Shengjia Lin; Michael Sabio; Geoffrey Greene; Benita S Katzenellenbogen; Sarat Chandarlapaty; John A Katzenellenbogen
Journal:  ACS Chem Biol       Date:  2018-11-26       Impact factor: 5.100

3.  Oral Selective Estrogen Receptor Downregulators (SERDs), a Breakthrough Endocrine Therapy for Breast Cancer.

Authors:  Donald P McDonnell; Suzanne E Wardell; John D Norris
Journal:  J Med Chem       Date:  2015-06-03       Impact factor: 7.446

4.  The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer.

Authors:  James D Joseph; Beatrice Darimont; Wei Zhou; Alfonso Arrazate; Amy Young; Ellen Ingalla; Kimberly Walter; Robert A Blake; Jim Nonomiya; Zhengyu Guan; Lorna Kategaya; Steven P Govek; Andiliy G Lai; Mehmet Kahraman; Dan Brigham; John Sensintaffar; Nhin Lu; Gang Shao; Jing Qian; Kate Grillot; Michael Moon; Rene Prudente; Eric Bischoff; Kyoung-Jin Lee; Celine Bonnefous; Karensa L Douglas; Jackaline D Julien; Johnny Y Nagasawa; Anna Aparicio; Josh Kaufman; Benjamin Haley; Jennifer M Giltnane; Ingrid E Wertz; Mark R Lackner; Michelle A Nannini; Deepak Sampath; Luis Schwarz; Henry Charles Manning; Mohammed Noor Tantawy; Carlos L Arteaga; Richard A Heyman; Peter J Rix; Lori Friedman; Nicholas D Smith; Ciara Metcalfe; Jeffrey H Hager
Journal:  Elife       Date:  2016-07-13       Impact factor: 8.140

5.  GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models.

Authors:  Shanchun Guo; Changde Zhang; Madhusoodanan Mottamal; Ahamed Hossain; Jiawang Liu; Guangdi Wang
Journal:  Breast Cancer Res Treat       Date:  2020-02-06       Impact factor: 4.872

6.  Rational Design of a Boron-Modified Triphenylethylene (GLL398) as an Oral Selective Estrogen Receptor Downregulator.

Authors:  Jiawang Liu; Shilong Zheng; Shanchun Guo; Changde Zhang; Qiu Zhong; Qiang Zhang; Peng Ma; Elena V Skripnikova; Melyssa R Bratton; Thomas E Wiese; Guangdi Wang
Journal:  ACS Med Chem Lett       Date:  2016-11-29       Impact factor: 4.345

7.  Tamoxifen Resistance Trumped and Oral Selective Estrogen Receptor Degraders Arrive.

Authors:  V Craig Jordan
Journal:  Clin Cancer Res       Date:  2018-04-19       Impact factor: 12.531

8.  Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells.

Authors:  Jian Min; Valeria Sanabria Guillen; Abhishek Sharma; Yuechao Zhao; Yvonne Ziegler; Ping Gong; Christopher G Mayne; Sathish Srinivasan; Sung Hoon Kim; Kathryn E Carlson; Kendall W Nettles; Benita S Katzenellenbogen; John A Katzenellenbogen
Journal:  J Med Chem       Date:  2017-07-14       Impact factor: 7.446

9.  New Class of Selective Estrogen Receptor Degraders (SERDs): Expanding the Toolbox of PROTAC Degrons.

Authors:  Lucia Wang; Valeria S Guillen; Naina Sharma; Kevin Flessa; Jian Min; Kathryn E Carlson; Weiyi Toy; Sara Braqi; Benita S Katzenellenbogen; John A Katzenellenbogen; Sarat Chandarlapaty; Abhishek Sharma
Journal:  ACS Med Chem Lett       Date:  2018-07-05       Impact factor: 4.345

10.  Novel Selective Estrogen Receptor Ligand Conjugates Incorporating Endoxifen-Combretastatin and Cyclofenil-Combretastatin Hybrid Scaffolds: Synthesis and Biochemical Evaluation.

Authors:  Patrick M Kelly; Niall O Keely; Sandra A Bright; Bassem Yassin; Gloria Ana; Darren Fayne; Daniela M Zisterer; Mary J Meegan
Journal:  Molecules       Date:  2017-08-31       Impact factor: 4.411
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.