Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Transplantation of isologous islets of Langerhans in diabetic rats.

Literature DB >> 820149

Transplantation of isologous islets of Langerhans in diabetic rats.

D Lorenz, K D Rosenbaum, J Petermann, M Ziegler, R Beckert, A Dorn.

Abstract

Isologous isolated islets of Langerhans were transplanted into the peritoneum and, via the portal vein, into the liver of diabetic rats. In both groups almost normal blood glucose and serum insulin levels were achieved for a period of three months. Glucose tolerance tests were markedly improved. Morphological examination of the transplanted islets and immunohistochemical tests for insulin and glucagon showed the liver to be a more suitable site for islet grafting than the peritoneum.

Entities: Chemical Disease Species

Mesh：

Substances：
Blood Glucose
Insulin

Year: 1975 PMID： 820149 DOI： 10.1007/BF02581110

Source DB: PubMed Journal: Acta Diabetol Lat ISSN： 0001-5563

8 in total

1. Total pancreatectomy in the rat: operation, effects, and postoperative care.

Authors: R O SCOW
Journal: Endocrinology Date: 1957-03 Impact factor: 4.736

2. Pancreatic islet transplantation in the rat.

Authors: R J Leonard; A Lazarow; O D Hegre
Journal: Diabetes Date: 1973-06 Impact factor: 9.461

Review 3. The Banting Memorial Lecture 1973: Islet differentiation, organ culture, and transplantation.

Authors: A Lazarow; L J Wells; A M Carpenter; O D Hegre; R J Leonard; R C McEvoy
Journal: Diabetes Date: 1973-12 Impact factor: 9.461

4. Transplantation of intact pancreatic islets in rats.

Authors: W F Ballinger; P E Lacy
Journal: Surgery Date: 1972-08 Impact factor: 3.982

5. Response of beta cells to different levels of glucose: fetal pancreases grown in organ culture and subsequently transplanted to maternal hosts.

Authors: O D Hegre; L J Wells; A Lazarow
Journal: Diabetes Date: 1970-12 Impact factor: 9.461

6. Site of glucagon in the islets of Langerhans of man as studied by the immunofluorescent technic.

Authors: R Lomský; F Langr; V Vortel
Journal: Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Date: 1968

7. Method for the isolation of intact islets of Langerhans from the rat pancreas.

Authors: P E Lacy; M Kostianovsky
Journal: Diabetes Date: 1967-01 Impact factor: 9.461

8. Effect of transplantation site on the results of pancreatic islet isografts in diabetic rats.

Authors: C B Kemp; M J Knight; D W Scharp; W F Ballinger; P E Lacy
Journal: Diabetologia Date: 1973-12 Impact factor: 10.122

8 in total

4 in total

Transplantation of isologous islets of Langerhans in diabetic rats.

1. Total pancreatectomy in the rat: operation, effects, and postoperative care.

2. Pancreatic islet transplantation in the rat.

Review 3. The Banting Memorial Lecture 1973: Islet differentiation, organ culture, and transplantation.

4. Transplantation of intact pancreatic islets in rats.

5. Response of beta cells to different levels of glucose: fetal pancreases grown in organ culture and subsequently transplanted to maternal hosts.

6. Site of glucagon in the islets of Langerhans of man as studied by the immunofluorescent technic.

7. Method for the isolation of intact islets of Langerhans from the rat pancreas.

8. Effect of transplantation site on the results of pancreatic islet isografts in diabetic rats.

Review 1. Alternative transplantation sites for pancreatic islet grafts.

Review 2. Pancreas and islet transplantation. I. Experimental studies.

3. Transplantation of isologous islets of Langerhans in diabetic rats. Long-term immunohistochemical results.

Review 4. Revascularization of transplanted pancreatic islets and role of the transplantation site.