| Literature DB >> 8201347 |
J I O'Riordan1, J Hutchinson, M X FitzGerald, M Hutchinson.
Abstract
Two patients developed a disabling amnesic syndrome after seizures associated with oral theophylline treatment. Such seizures are more likely in the elderly, in the presence of pre-existing neurological disease, and when theophylline is given with certain antibiotics and cimetidine. The mechanism of neuronal injury may be by the excessive release of endogenous excitotoxic glutamate.Entities:
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Year: 1994 PMID： 8201347 PMCID： PMC1072938 DOI： 10.1136/jnnp.57.5.643
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154