| Literature DB >> 8201339 |
F G van der Meché1, J M Bogaard, J C van der Sluys, R J Schimsheimer, C C Ververs, H F Busch.
Abstract
Daytime sleepiness is common in myotonic dystrophy and might be attributed to disturbed nocturnal breathing. Seventeen out of 22 patients complained of excessive daytime sleepiness, resembling "idiopathic hypersomnolence". Sleep apnoea might have contributed to daytime sleepiness in only three of 17 patients. Treatment with the central stimulant methylphenidate produced sustained benefit in seven out of 11 patients tested. Daytime sleepiness in myotonic dystrophy is usually caused by dysfunction of central sleep regulation and not by disturbed nocturnal breathing.Entities:
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Year: 1994 PMID: 8201339 PMCID: PMC1072930 DOI: 10.1136/jnnp.57.5.626
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN: 0022-3050 Impact factor: 10.154