Literature DB >> 8199468

Determination of tylosin and tilmicosin residues in animal tissues by reversed-phase liquid chromatography.

W Chan1, G C Gerhardt, C D Salisbury.   

Abstract

A method for the simultaneous determination of tylosin and tilmicosin residues in animal tissues is reported. Solid-phase extraction columns are used to isolate the drugs from tissue extracts. Determination is accomplished by reversed-phase liquid chromatography with UV detection at 287 nm. Mean recoveries from spiked tissues were 79.9% (coefficient of variation [CV], 8.1%) for tylosin and 92.6% (CV, 8.7%) for tilmicosin. Detection limits for tylosin and tilmicosin were 0.020 and 0.010 ppm, respectively.

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Year:  1994        PMID: 8199468

Source DB:  PubMed          Journal:  J AOAC Int        ISSN: 1060-3271            Impact factor:   1.913


  1 in total

1.  The effect of administering long-acting oxytetracycline and tilmicosin either by dart gun or by hand on injection site lesions and drug residues in beef cattle.

Authors:  J Van Donkersgoed; M VanderKop; C Salisbury; L Sears; J Holowath
Journal:  Can Vet J       Date:  1999-08       Impact factor: 1.008

  1 in total

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