Literature DB >> 8198389

Mechanism of epilepsy.

C Shin1, J O McNamara.   

Abstract

Epilepsy is a collection of diverse disorders that together affect approximately 1% of the general population. Current therapies are largely symptomatic and are aimed at controlling seizures in affected individuals. This review focuses on emerging insights into mechanisms underlying the most common form of epilepsy--complex partial epilepsy--and also addresses progress in molecular genetic approaches. Such developments will hopefully lead to more effective therapies.

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Year:  1994        PMID: 8198389     DOI: 10.1146/annurev.med.45.1.379

Source DB:  PubMed          Journal:  Annu Rev Med        ISSN: 0066-4219            Impact factor:   13.739


  7 in total

1.  Manganese-enhanced magnetic resonance imaging detects mossy fiber sprouting in the pilocarpine model of epilepsy.

Authors:  Jackeline M Malheiros; Roberson S Polli; Fernando F Paiva; Beatriz M Longo; Luiz E Mello; Afonso C Silva; Alberto Tannús; Luciene Covolan
Journal:  Epilepsia       Date:  2012-05-29       Impact factor: 5.864

2.  Preparation of Nanocrystals for Insoluble Drugs by Top-Down Nanotechnology with Improved Solubility and Bioavailability.

Authors:  Xun Zhang; Zhiguo Li; Jing Gao; Zengming Wang; Xiang Gao; Nan Liu; Meng Li; Hui Zhang; Aiping Zheng
Journal:  Molecules       Date:  2020-02-28       Impact factor: 4.411

3.  Network-level analysis of cortical thickness of the epileptic brain.

Authors:  A Raj; S G Mueller; K Young; K D Laxer; M Weiner
Journal:  Neuroimage       Date:  2010-05-27       Impact factor: 6.556

Review 4.  Gadd45 in Neuronal Development, Function, and Injury.

Authors:  Faraz A Sultan; Bassel E Sawaya
Journal:  Adv Exp Med Biol       Date:  2022       Impact factor: 2.622

5.  Wavelet-based Gaussian-mixture hidden Markov model for the detection of multistage seizure dynamics: a proof-of-concept study.

Authors:  Alan Wl Chiu; Miron Derchansky; Marija Cotic; Peter L Carlen; Steuart O Turner; Berj L Bardakjian
Journal:  Biomed Eng Online       Date:  2011-04-19       Impact factor: 2.819

Review 6.  Advantages of Structure-Based Drug Design Approaches in Neurological Disorders.

Authors:  Murali Aarthy; Umesh Panwar; Chandrabose Selvaraj; Sanjeev Kumar Singh
Journal:  Curr Neuropharmacol       Date:  2017-11-14       Impact factor: 7.363

7.  The role of reactive species in epileptogenesis and influence of antiepileptic drug therapy on oxidative stress.

Authors:  Boštjan Martinc; Iztok Grabnar; Tomaž Vovk
Journal:  Curr Neuropharmacol       Date:  2012-12       Impact factor: 7.363

  7 in total

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