Research trends in Alzheimer's disease.

Alzheimer's disease (AD) is a tragic condition. The individual experiencing the loss of memory, difficulty with language, change in personality, and disturbance in behavior associated with AD is not alone; the number of people with AD is estimated at 4 million; by the year 2050, as many as 14 million Americans may be afflicted (National Institute of Aging, 1992). AD is the fourth leading cause of death for adults, taking more than 100,000 lives annually. The families of these patients also are victims, as they watch their loved ones slowly forget them and all that was once meaningful in their lives.