Literature DB >> 8194280

Pharmacokinetic considerations in rational drug design.

M Gumbleton1, W Sneader.   

Abstract

Mesh：

Year:  1994        PMID： 8194280     DOI： 10.2165/00003088-199426030-00001

Source DB:  PubMed          Journal:  Clin Pharmacokinet        ISSN： 0312-5963            Impact factor:   6.447


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  22 in total

1.  A redox-based system that enhances delivery of estradiol to the brain: pharmacokinetic evaluation in the dog.

Authors:  K Dietzel; V Keuth; K S Estes; M E Brewster; R M Clemmons; R Vistelle; N S Bodor; H Derendorf
Journal:  Pharm Res       Date:  1990-08       Impact factor: 4.200

2.  CLINICAL PHARMACOLOGY OF 2-SULFANILAMIDO-3-METHOXYPYRAZINE.

Authors:  R L HERTING; F LOPEZ; E SCHERFLING; J C SYLVESTER; R WIEGAND
Journal:  Antimicrob Agents Chemother (Bethesda)       Date:  1964

3.  The influence of peptide structure on transport across Caco-2 cells.

Authors:  R A Conradi; A R Hilgers; N F Ho; P S Burton
Journal:  Pharm Res       Date:  1991-12       Impact factor: 4.200

Review 4.  Prodrugs. Do they have advantages in clinical practice?

Authors:  V J Stella; W N Charman; V H Naringrekar
Journal:  Drugs       Date:  1985-05       Impact factor: 9.546

5.  Comparative toxicological, chemotherapeutic and pharmacokinetic studies with sulphormethoxine and other sulphonamides in animals and man.

Authors:  E Böhni; B Fust; J Rieder; K Schaerer; L Havas
Journal:  Chemotherapy       Date:  1969       Impact factor: 2.544

6.  The metabolites of 14C-sulpiride in the rat.

Authors:  K Dross
Journal:  Arzneimittelforschung       Date:  1978

7.  Antipsychotic effect of remoxipride, a new substituted benzamide with selective antidopaminergic activity.

Authors:  A Lund Laursen; J Gerlach
Journal:  Acta Psychiatr Scand       Date:  1986-01       Impact factor: 6.392

8.  Validation of different microdialysis methods for the determination of unbound steady-state concentrations of theophylline in blood and brain tissue.

Authors:  P Sjöberg; I M Olofsson; T Lundqvist
Journal:  Pharm Res       Date:  1992-12       Impact factor: 4.200

9.  Quinolone antibacterial agents: relationship between structure and in vitro inhibition of the human cytochrome P450 isoform CYP1A2.

Authors:  U Fuhr; G Strobl; F Manaut; E M Anders; F Sörgel; E Lopez-de-Brinas; D T Chu; A G Pernet; G Mahr; F Sanz
Journal:  Mol Pharmacol       Date:  1993-02       Impact factor: 4.436

10.  Solid state conformations and antidopaminergic effects of remoxipride hydrochloride and a closely related salicylamide, FLA 797, in relation to dopamine receptor models.

Authors:  T Högberg; S Rämsby; T de Paulis; B Stensland; I Csöregh; A Wägner
Journal:  Mol Pharmacol       Date:  1986-10       Impact factor: 4.436
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  2 in total

Review 1.  The influence of food on the absorption and metabolism of drugs: an update.

Authors:  L Williams; D P Hill; J A Davis; D T Lowenthal
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1996 Jul-Sep       Impact factor: 2.441

2.  Lack of in vitro-in vivo correlation of a novel investigational anticancer agent, SH 30.

Authors:  Srinivasu Poondru; Ralph E Parchment; Vivek Purohit; Patricia LoRusso; Jerome P Horwitz; Stuart T Hazeldine; Lisa Polin; Thomas Corbett; Bhaskara R Jasti
Journal:  Invest New Drugs       Date:  2002-02       Impact factor: 3.850
  2 in total

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