Literature DB >> 8193237

[Jaundice secondary to intrahepatic deposit of light chains as a presenting form of multiple myeloma].

M D Macías Robles1, J M Navia-Osorio García-Braga, J L Menéndez Caro, J Velasco Alonso, I López Lagunas.   

Abstract

In the disease caused by deposit of light chains, nephropathy is the earlier and most frequent clinical manifestation; and although the liver is the extrarenal organ most frequently affected, its affection is rare without renal deposit of light chains. Bearing this in mind, we present the clinical and evolutive characteristics of a patient diagnosed of IgG Kappa multiple myeloma, whose first manifestation was a jaundice syndrome with intrahepatic deposit of light chains documented in the anatomopathologic study and in which, despite presenting renal failure, deposits of light chains were not observed in the renal biopsy. We review the medical literature on this topic.

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Year:  1994        PMID: 8193237

Source DB:  PubMed          Journal:  An Med Interna        ISSN: 0212-7199


  2 in total

1.  Hepatic failure caused by plasma cell infiltration in multiple myeloma.

Authors:  Fadi-E Rahhal; Robert-R Schade; Asha Nayak; Teresa A Coleman
Journal:  World J Gastroenterol       Date:  2009-04-28       Impact factor: 5.742

2.  Multiple myeloma in a patient with fever of unknown origin and cholestasis.

Authors:  Nicola Mumoli; Marco Cei; Roberto Incensati; Serena Verzuri
Journal:  CMAJ       Date:  2004-06-08       Impact factor: 8.262

  2 in total

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