Literature DB >> 81927

Controlled trial of hyposensitisation to Dermatophagoides pteronyssinus in children with asthma.

J O Warner, J F Price, J F Soothill, E N Hey.   

Abstract

Hyposensitisation with Dermatophagoides pteronyssinus tyrosine absorbate in asthmatic children with bronchial sensitivity to D. pteronyssinus was effective in a 12-month double-blind controlled clinical trial. Compared with controls, treated children used a smaller quantity of drugs while maintaining clinical and lung function improvements. In most children who improved there was no change in immediate response to D. pteronyssinus on bronchial provocation test, but the late reaction was lost in half the patients and these showed the greatest improvement in symptoms.

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Year:  1978        PMID: 81927     DOI: 10.1016/s0140-6736(78)91630-6

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  50 in total

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Review 5.  Desensitisation today.

Authors:  N Eiser
Journal:  BMJ       Date:  1990-06-02

Review 6.  Immunotherapy in asthma.

Authors:  J A Douglass; F C Thien; R E O'Hehir
Journal:  Thorax       Date:  1997-08       Impact factor: 9.139

7.  Hyposensitisation.

Authors:  J O Warner; J W Kerr
Journal:  Br Med J (Clin Res Ed)       Date:  1987-05-09

8.  Desensitising vaccines: an allergist's view.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1986-11-01

9.  A single dose desensitization for summer hay fever. Results of a double blind study-1988.

Authors:  P Fell; J Brostoff
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

10.  Economic evaluation of specific immunotherapy versus symptomatic treatment of allergic rhinitis in Germany.

Authors:  P K Schädlich; J G Brecht
Journal:  Pharmacoeconomics       Date:  2000-01       Impact factor: 4.981

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