Literature DB >> 8190556

Antimicrobial drug suspensions: a blinded comparison of taste of twelve common pediatric drugs including cefixime, cefpodoxime, cefprozil and loracarbef.

D M Demers1, D S Chan, J W Bass.   

Abstract

We conducted a blinded taste test evaluating 12 antimicrobial suspensions by smell, texture, taste, aftertaste and overall acceptance. Drugs received cumulative scores in each category as well as a total score ranking. Overall Lorabid scored highest but not significantly higher than Keflex, Suprax and Ceclor, all of which score higher than the other test drugs. Cefzil and Augmentin scored just below this group of drugs and higher than all other test drugs. Vantin was inferior to these drugs primarily because of its low score in aftertaste. It was ranked along with V-Cillin-K, Veetids, Sulfatrim and Pediazole, the lowest scoring group of drugs other than Dynapen which scored lower than all other test drugs. No difference overall was detected between the two penicillin VK suspensions evaluated, V-Cillin-K and Veetids.

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Year:  1994        PMID: 8190556

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN: 0891-3668            Impact factor:   2.129


  4 in total

1.  Study of the acceptability of antibiotic syrups, suspensions, and oral solutions prescribed to pediatric outpatients.

Authors:  Robert Cohen; France de La Rocque; Aurélie Lécuyer; Claudie Wollner; Marie Josée Bodin; Alain Wollner
Journal:  Eur J Pediatr       Date:  2008-10-29       Impact factor: 3.183

Review 2.  Rational prescribing of antibacterials in ambulatory children.

Authors:  J E Hoppe
Journal:  Pharmacoeconomics       Date:  1996-12       Impact factor: 4.981

3.  Stability, dose uniformity, and palatability of three counterterrorism drugs-human subject and electronic tongue studies.

Authors:  Nakissa Sadrieh; James Brower; Lawrence Yu; William Doub; Arthur Straughn; Stella Machado; Frank Pelsor; Emmanuelle Saint Martin; Terry Moore; John Reepmeyer; Duckhee Toler; Agnes Nguyenpho; Rosemary Roberts; Donald J Schuirmann; Moheb Nasr; Lucinda Buhse
Journal:  Pharm Res       Date:  2005-09-22       Impact factor: 4.200

Review 4.  Practical considerations when treating children with antimicrobials in the outpatient setting.

Authors:  L N Werk; H Bauchner
Journal:  Drugs       Date:  1998-06       Impact factor: 9.546

  4 in total

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