Literature DB >> 8190473

Epithelial ingrowth and glaucoma drainage implants.

P A Sidoti1, D S Minckler, G Baerveldt, P P Lee, D K Heuer.   

Abstract

BACKGROUND: The authors report four cases of conjunctival epithelial invasion into the fibrous capsule surrounding a Baerveldt glaucoma implant. All cases were associated with concurrent or recent prior scleral buckling surgery.
METHODS: Three patients had postoperative conjunctival wound leaks, one in the immediate postoperative period and the other two at 9 and 17 days postoperatively after release of the tube ligature. In the fourth patient, a fistulous tract developed over the implant after a first-stage insertion. Histopathologic confirmation of subconjunctival epithelialization was obtained in two of these patients.
RESULTS: Surgical revision was performed in all patients. Excision and debridement of all epithelium-lined subconjunctival tissues and extensive bipolar cautery were used in the three patients with wound leaks. Implant removal also was performed in one of these. Fistulectomy and bipolar cautery were used in the fourth patient. No recurrent wound leaks or other adverse sequelae were noted.
CONCLUSIONS: Epithelial invasion of the subconjunctival space and inner bleb wall after implantation of glaucoma drainage devices can lead to breakdown of the conjunctival wound and persistent aqueous leak. Prior or concurrent scleral buckling surgery may predispose to this occurrence. Surgical revision involving epithelial debridement, cautery, and meticulous wound closure, with or without implant removal, has been used successfully in the management of this complication.

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Mesh:

Year:  1994        PMID: 8190473     DOI: 10.1016/s0161-6420(94)31245-0

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  4 in total

1.  Efficacy and safety of the Ahmed glaucoma valve implant in Chinese eyes with complicated glaucoma.

Authors:  J S Lai; A S Poon; J K Chua; C C Tham; A T Leung; D S Lam
Journal:  Br J Ophthalmol       Date:  2000-07       Impact factor: 4.638

2.  Diagnostic pars plana vitrectomy report of a 21-year retrospective study.

Authors:  G N Palexas; W R Green; M F Goldberg; Y Ding
Journal:  Trans Am Ophthalmol Soc       Date:  1995

3.  One-Year Feasibility Study of Replenish MicroPump for Intravitreal Drug Delivery: A Pilot Study.

Authors:  Juan-Carlos Gutiérrez-Hernández; Sean Caffey; Walid Abdallah; Phillip Calvillo; Roberto González; Jason Shih; Jeff Brennan; Jenna Zimmerman; Juan-Carlos Martínez-Camarillo; Anthony R Rodriguez; Rohit Varma; Arturo Santos; Gisela Sánchez; Mark Humayun
Journal:  Transl Vis Sci Technol       Date:  2014-07-01       Impact factor: 3.283

4.  Management of severe epithelial versus fibrous downgrowth following trabeculectomy: Case report and literature review.

Authors:  Christos N Theophanous; Ema Avdagic; Asim V Farooq; Dimitra Skondra; Mary Qiu
Journal:  Am J Ophthalmol Case Rep       Date:  2021-07-27
  4 in total

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