Literature DB >> 8189539

Glycosylphosphatidylinositol-anchored CD4 supports human immunodeficiency virus type 1 replication, but not cytopathic effect, in T-cell transfectants.

W L Marshall1, E S Mittler, P Avery, J P Lawrence, R W Finberg.   

Abstract

Despite equivalent p24 antigen production, HSB-2 T cells expressing glycosylphosphatidylinositol (GPi)-linked CD4 were productively infected without cell death or syncytium formation, unlike HSB-2 transfectants expressing wild-type CD4 (wtCD4). HSB-2 transfectants dually expressing wtCD4 and GPi-linked CD4 formed syncytia and died. Thus, wtCD4 expression is critical for human immunodeficiency virus cytopathic effect in HSB-2 transfectants.

Entities:  

Mesh:

Substances:

Year:  1994        PMID: 8189539      PMCID: PMC236913     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  36 in total

1.  Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity.

Authors:  J Sodroski; W C Goh; C Rosen; K Campbell; W A Haseltine
Journal:  Nature       Date:  1986 Jul 31-Aug 6       Impact factor: 49.962

2.  Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck.

Authors:  A Veillette; M A Bookman; E M Horak; L E Samelson; J B Bolen
Journal:  Nature       Date:  1989-03-16       Impact factor: 49.962

3.  Neuropathology of acquired immunodeficiency syndrome (AIDS): an autopsy review.

Authors:  C K Petito; E S Cho; W Lemann; B A Navia; R W Price
Journal:  J Neuropathol Exp Neurol       Date:  1986-11       Impact factor: 3.685

4.  HIV infection does not require endocytosis of its receptor, CD4.

Authors:  P J Maddon; J S McDougal; P R Clapham; A G Dalgleish; S Jamal; R A Weiss; R Axel
Journal:  Cell       Date:  1988-09-09       Impact factor: 41.582

5.  Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.

Authors:  H Potter; L Weir; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1984-11       Impact factor: 11.205

6.  Comparison of T cell receptor alpha, beta, and gamma gene rearrangement and expression in T cell acute lymphoblastic leukemia.

Authors:  J Hara; S H Benedict; E Champagne; T W Mak; M Minden; E W Gelfand
Journal:  J Clin Invest       Date:  1988-04       Impact factor: 14.808

7.  The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.

Authors:  C E Rudd; J M Trevillyan; J D Dasgupta; L L Wong; S F Schlossman
Journal:  Proc Natl Acad Sci U S A       Date:  1988-07       Impact factor: 11.205

8.  Cell-specific heterogeneity in sensitivity of phosphatidylinositol-anchored membrane antigens to release by phospholipase C.

Authors:  M G Low; J Stiernberg; G L Waneck; R A Flavell; P W Kincade
Journal:  J Immunol Methods       Date:  1988-10-04       Impact factor: 2.303

9.  Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS.

Authors:  M Popovic; M G Sarngadharan; E Read; R C Gallo
Journal:  Science       Date:  1984-05-04       Impact factor: 47.728

10.  Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes.

Authors:  H E Gendelman; J M Orenstein; M A Martin; C Ferrua; R Mitra; T Phipps; L A Wahl; H C Lane; A S Fauci; D S Burke
Journal:  J Exp Med       Date:  1988-04-01       Impact factor: 14.307

View more
  2 in total

1.  Human immunodeficiency virus type 1 Nef increases the efficiency of reverse transcription in the infected cell.

Authors:  O Schwartz; V Maréchal; O Danos; J M Heard
Journal:  J Virol       Date:  1995-07       Impact factor: 5.103

2.  Postbinding events mediated by human immunodeficiency virus type 1 are sensitive to modifications in the D4-transmembrane linker region of CD4.

Authors:  S Moir; J Perreault; L Poulin
Journal:  J Virol       Date:  1996-11       Impact factor: 5.103

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.