Literature DB >> 8189256

Stereotactic radiosurgery for acoustic nerve tumors in patients with useful preoperative hearing: results at 2-year follow-up examination.

O K Ogunrinde1, L D Lunsford, J C Flickinger, D Kondziolka.   

Abstract

Twenty patients with acoustic nerve tumors (mean diameter < or = 30 mm) and useful preoperative hearing were examined 2 years after stereotactic radiosurgery to determine the effectiveness of the surgery in the control of tumor growth and the preservation of cranial nerve function. Results showed tumor volume stabilization (12 cases) or reduction (seven cases) was achieved in a total of 19 patients (95%). Useful hearing (defined as Gardner and Robertson Class I or II) preservation was obtained in 100% of cases immediately postoperatively, 50% at 6 months, and 45% at both 1 and 2 years. Two years after stereotactic radiosurgery, facial nerve function was preserved in 90% of patients and 75% continued to have normal trigeminal nerve function. All patients returned to and maintained their preoperative functional status within 3 to 5 days after radiosurgery. These findings indicate that stereotactic radiosurgery with multiple isocenters and narrow radiation beams is a safe and effective management strategy for progressive acoustic nerve tumors. Auditory, facial, and trigeminal nerve function can be preserved in most patients. Prevention of further growth and preservation of cranial nerve function appear to be satisfactory goals in the current management of patients with acoustic neuromas.

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Year:  1994        PMID: 8189256     DOI: 10.3171/jns.1994.80.6.1011

Source DB:  PubMed          Journal:  J Neurosurg        ISSN: 0022-3085            Impact factor:   5.115


  3 in total

1.  Acoustic Neuromas.

Authors:  Douglas Kondziolka; L. Dade Lunsford; John C. Flickinger
Journal:  Curr Treat Options Neurol       Date:  2002-03       Impact factor: 3.598

2.  Prospective study on the dose distribution to the acoustic structures during postoperative 3D conformal radiotherapy for parotid tumors: dosimetric and audiometric aspects.

Authors:  Barbara A Jereczek-Fossa; Elena Rondi; Andrzej Zarowski; Alberto D'Onofrio; Daniela Alterio; Mario Ciocca; Livia Corinna Bianchi; Marco Krengli; Luca Calabrese; Mohssen Ansarin; Gioacchino Giugliano; Roberto Orecchia
Journal:  Strahlenther Onkol       Date:  2011-05-16       Impact factor: 3.621

3.  Interstitial radiotherapy of 25 parasellar/clival meningiomas and 19 meningiomas in the elderly. Analysis of short-term tolerance and responses.

Authors:  V Vuorinen; J Heikkonen; A Brander; K Setälä; T Sane; T Randell; A Paetau; J Pohjola; M Mäntylä; J Jääskeläinen
Journal:  Acta Neurochir (Wien)       Date:  1996       Impact factor: 2.216

  3 in total

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