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Literature DB >> 8188

Effect of atenolol on ventilatory and cardiac function in asthma.

Abstract

The effects on ventilatory and cardiac function of atenolol, a new cardioselective beta-adrenoceptor blocking agent, were compared with those of practolol in a double-blind trial in 12 patients with asthma. Both drugs impaired ventilatory function--atenolol insignificantly and practolol significantly. Atenolol was if anything more cardioselective than practolol. Neither drug interfered significantly with the bronchodilator response to inhaled isoprenaline. Atenolol is suitable for use in patients for whom practolol would formerly have been chosen because of its cardioselectivity.

Entities: Chemical Disease Species

Mesh：

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Year: 1976 PMID： 8188 PMCID： PMC1687593 DOI： 10.1136/bmj.2.6033.453

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

10 in total

1. An investigation into the cardiac and pulmonary beta-adrenoceptor blocking activity of ICI 66,082 in man.

Authors: G E Marlin; C R Kumana; C M Kaye; D M Smith; P Turner
Journal: Br J Clin Pharmacol Date: 1975-04 Impact factor: 4.335

2. Comparison of the effects on airway conductance of a new selective beta-adrenergic blocking drug, atenolol, and propranolol in asthmatic subjects.

Authors: H Aström
Journal: Scand J Respir Dis Date: 1975

3. Selective cardiac sympathetic blockade as an adjunct to bronchodilator therapy.

Authors: R Powles; E Shinebourne; J Hamer
Journal: Thorax Date: 1969-09 Impact factor: 9.139

4. Practolol in the treatment of tachyarrhythmias in patients with bronchial asthma.

Authors: H Formgren
Journal: Am Heart J Date: 1972-11 Impact factor: 4.749

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Authors: H M Beumer; H J Hardonk
Journal: Med Klin Date: 1971-12-24

6. Significance of effect of beta blockade on ventilatory function in normal and asthmatic subjects.

Authors: R S Jones
Journal: Thorax Date: 1972-09 Impact factor: 9.139

7. A comparison of the effect on airway resistance of a new beta blocking drug, ICI.50,172 and propranolol.

Authors: A G Macdonald; R S McNeill
Journal: Br J Anaesth Date: 1968-07 Impact factor: 9.166

8. Effect of new beta-adrenergic blocking agent, Atenolol (Tenormin), on pain frequency, trinitrin consumption, and exercise ability.

Authors: P Roy; L Day; E Sowton
Journal: Br Med J Date: 1975-07-26

9. Human pharmacokinetic and pharmacodynamic studies on the atenolo (ICI 66,082), a new cardioselective beta-adrenoceptor blocking drug.

Authors: F J Conway; J D Fitzgerald; J McAinsh; D J Rowlands; W T Simpson
Journal: Br J Clin Pharmacol Date: 1976-04 Impact factor: 4.335

10. Beta1-blocker (practolol) and exercise in patients with chronic obstructive lung disease.

Authors: J Schaanning; J S Vilsvik
Journal: Acta Med Scand Date: 1976

10 in total

23 in total

1. Beta-adrenoceptor antagonists and respiratory function.

Authors: D G McDevitt
Journal: Br J Clin Pharmacol Date: 1978-08 Impact factor: 4.335

Review 2. The assessment of beta-adrenoceptor blocking drugs in man.

Authors: D G McDevitt
Journal: Br J Clin Pharmacol Date: 1977-08 Impact factor: 4.335

3. beta-Adrenoceptor antagonists and respiratory function.

Authors: D G McDevitt
Journal: Br J Clin Pharmacol Date: 1978-02 Impact factor: 4.335

4. Beta-blockers and asthma.

Authors: P B Decalmer; S S Chatterjee; J M Cruickshank; M K Benson; G M Sterling
Journal: Br Heart J Date: 1978-02

5. Effect of partial agonist activity on the side effects of beta-blockade in patients with chronic stable angina.

Authors: J Chambers; M L Ong; F Akhras; G Adam; G Jackson
Journal: Drugs Date: 1989 Impact factor: 9.546

6. Assessment of airways, tremor and chronotropic responses to inhaled salbutamol in the quantification of beta 2-adrenoceptor blockade.

Authors: B J Lipworth; R A Brown; D G McDevitt
Journal: Br J Clin Pharmacol Date: 1989-07 Impact factor: 4.335