Literature DB >> 8187867

Regulatory squelching.

M A Cahill1, W H Ernst, R Janknecht, A Nordheim.   

Abstract

An important function of transcription factors may be to sequester coactivators or corepressors of transcription. In this manner transcription factors could regulate in trans the activity of promoters to which they do not bind. This may be of widespread significance as a mechanism to control cell cycle-dependent and differentiation-specific transcriptional activity within eukaryotic cells. Therefore squelching in vivo may be important than hitherto appreciated.

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Year:  1994        PMID： 8187867     DOI： 10.1016/0014-5793(94)00320-3

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  25 in total

1.  Repression of Ets-2-induced transactivation of the tau interferon promoter by Oct-4.

Authors:  T Ezashi; D Ghosh; R M Roberts
Journal:  Mol Cell Biol       Date:  2001-12       Impact factor: 4.272

Review 2.  Intrinsic and Extrinsic Factors Governing the Transcriptional Regulation of ESR1.

Authors:  David K Lung; Rebecca M Reese; Elaine T Alarid
Journal:  Horm Cancer       Date:  2020-06-26       Impact factor: 3.869

3.  Progesterone receptor-A and -B have opposite effects on proinflammatory gene expression in human myometrial cells: implications for progesterone actions in human pregnancy and parturition.

Authors:  Huiqing Tan; Lijuan Yi; Neal S Rote; William W Hurd; Sam Mesiano
Journal:  J Clin Endocrinol Metab       Date:  2012-03-14       Impact factor: 5.958

4.  Identification of the early VIP-regulated transcriptome and its associated, interactome in resting and activated murine CD4 T cells.

Authors:  Sheri Tinnell Dorsam; Emilie Vomhof-Dekrey; Rebecca J Hermann; Jodie S Haring; Travis Van der Steen; Erich Wilkerson; Goran Boskovic; James Denvir; Yulia Dementieva; Donald Primerano; Glenn Paul Dorsam
Journal:  Mol Immunol       Date:  2010-02-01       Impact factor: 4.407

5.  The Prozone Effect Accounts for the Paradoxical Function of the Cdk-Binding Protein Suc1/Cks.

Authors:  Sang Hoon Ha; Sun Young Kim; James E Ferrell
Journal:  Cell Rep       Date:  2016-02-04       Impact factor: 9.423

6.  Refined spatial manipulation of neuronal function by combinatorial restriction of transgene expression.

Authors:  Haojiang Luan; Nathan C Peabody; Charles R Vinson; Benjamin H White
Journal:  Neuron       Date:  2006-11-09       Impact factor: 17.173

7.  The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator.

Authors:  Lucie Hyrsova; Tomas Smutny; Alejandro Carazo; Stefan Moravcik; Jana Mandikova; Frantisek Trejtnar; Sabine Gerbal-Chaloin; Petr Pavek
Journal:  Br J Pharmacol       Date:  2016-04-08       Impact factor: 8.739

8.  Epstein-Barr virus nuclear antigen 3C is a transcriptional regulator.

Authors:  D Marshall; C Sample
Journal:  J Virol       Date:  1995-06       Impact factor: 5.103

9.  Tissue-restricted transcription from a conserved intragenic CpG island in the Klf1 gene in mice.

Authors:  Cherie M Southwood; Leonard Lipovich; Alexander Gow
Journal:  Biol Reprod       Date:  2012-11-01       Impact factor: 4.285

10.  The active form of human aryl hydrocarbon receptor (AHR) repressor lacks exon 8, and its Pro 185 and Ala 185 variants repress both AHR and hypoxia-inducible factor.

Authors:  Sibel I Karchner; Matthew J Jenny; Ann M Tarrant; Brad R Evans; Hyo Jin Kang; Insoo Bae; David H Sherr; Mark E Hahn
Journal:  Mol Cell Biol       Date:  2009-04-20       Impact factor: 4.272
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