Literature DB >> 8187791

Effect of antimicrobial and antineoplastic drugs on the uptake of fluconazole by human neutrophils and tissue culture cells.

I García1, A Pascual, C Conejo, J Salvador, E J Perea.   

Abstract

The effect of eight antimicrobial and three antineoplastic drugs on the uptake of fluconazole by human neutrophils and culture epithelial cells was evaluated. Fluconazole reached higher concentrations intracellularly than extracellularly (cellular to extracellular concentration ratio C/E > or = 1.3) in the presence of therapeutical concentrations of the antimicrobial and antineoplastic agents evaluated.

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Year:  1993        PMID： 8187791     DOI： 10.1007/bf01992170

Source DB:  PubMed          Journal:  Eur J Clin Microbiol Infect Dis        ISSN： 0934-9723            Impact factor:   3.267


  11 in total

1.  Effect of antimicrobial and antineoplastic drugs alone and in combination on the phagocytic and candidacidal function of human polymorphonuclear leucocytes.

Authors:  C J Pallister; D W Warnock
Journal:  J Antimicrob Chemother       Date:  1989-01       Impact factor: 5.790

2.  Fluorometric measurement of ofloxacin uptake by human polymorphonuclear leukocytes.

Authors:  A Pascual; I Garcia; E J Perea
Journal:  Antimicrob Agents Chemother       Date:  1989-05       Impact factor: 5.191

3.  Quantitative relationships between circulating leukocytes and infection in patients with acute leukemia.

Authors:  G P Bodey; M Buckley; Y S Sathe; E J Freireich
Journal:  Ann Intern Med       Date:  1966-02       Impact factor: 25.391

Review 4.  Effects of antimicrobial and antineoplastic drugs on the phagocytic and microbicidal function of the polymorphonuclear leukocyte.

Authors:  L A Mandell
Journal:  Rev Infect Dis       Date:  1982 May-Jun

Review 5.  Infectious complications in leukemic patients.

Authors:  G P Bodey; R Bolivar; V Fainstein
Journal:  Semin Hematol       Date:  1982-07       Impact factor: 3.851

6.  Effect of methotrexate alone and in combination with antifungal drugs on the growth of Candida albicans.

Authors:  D W Warnock; E M Johnson; J Burke; R Pracharktam
Journal:  J Antimicrob Chemother       Date:  1989-06       Impact factor: 5.790

7.  Drug interactions with fluconazole.

Authors:  J D Lazar; K D Wilner
Journal:  Rev Infect Dis       Date:  1990 Mar-Apr

8.  Uptake and intracellular activity of fluconazole in human polymorphonuclear leukocytes.

Authors:  A Pascual; I García; C Conejo; E J Perea
Journal:  Antimicrob Agents Chemother       Date:  1993-02       Impact factor: 5.191

9.  Fungal infections in cancer patients: an international autopsy survey.

Authors:  G Bodey; B Bueltmann; W Duguid; D Gibbs; H Hanak; M Hotchi; G Mall; P Martino; F Meunier; S Milliken
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1992-02       Impact factor: 3.267

10.  Bacteremias and fungemias in oncologic patients with central venous catheters: changing spectrum of infection.

Authors:  J N Lowder; H M Lazarus; R H Herzig
Journal:  Arch Intern Med       Date:  1982-08
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