Literature DB >> 8184767

Myocardial collagen and its functional role.

J S Janicki1, B B Matsubara, A Kabour.   

Abstract

Even though normally present in relatively small amounts, myocardial collagen strongly influences ventricular diastolic function. Removal of less than half of the normal amount results in a dilated ventricle with increased compliance. In contrast, an abnormal increase in collagen concentration results in a stiffer myocardium and ventricular diastolic dysfunction.

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Year:  1993        PMID: 8184767     DOI: 10.1007/978-1-4615-2946-0_28

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  2 in total

Review 1.  Matrix metalloproteinases in the progression of heart failure: potential therapeutic implications.

Authors:  Y Y Li; A M Feldman
Journal:  Drugs       Date:  2001       Impact factor: 9.546

2.  Cardioprotective effects of lysyl oxidase inhibition against volume overload-induced extracellular matrix remodeling.

Authors:  Elia C El Hajj; Milad C El Hajj; Van K Ninh; Jason D Gardner
Journal:  Exp Biol Med (Maywood)       Date:  2015-11-17
  2 in total

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