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Literature DB >> 8183569

The Unp proto-oncogene encodes a nuclear protein.

Abstract

The mouse Unp gene is related to TRE17, a human oncogene, but is not its mouse homolog. Unp is a ubiquitously expressed gene producing two related mRNAs. The protein product of Unp is localized in the nucleus. Expression of Unp from a highly active promoter results in tumorigenic transformation of NIH3T3 cells injected into athymic mice. Unp therefore encodes a novel nuclear oncoprotein.

Entities: Gene Species

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Year: 1994 PMID： 8183569

Source DB: PubMed Journal: Oncogene ISSN： 0950-9232 Impact factor: 9.867

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Cited

14 in total

1. Tissue-specificity, functional characterization and subcellular localization of a rat ubiquitin-specific processing protease, UBP109, whose mRNA expression is developmentally regulated.

Authors: K C Park; E J Choi; S W Min; S S Chung; H Kim; T Suzuki; K Tanaka; C H Chung
Journal: Biochem J Date: 2000-07-15 Impact factor: 3.857

Review 2. Ubiquitin-mediated proteolysis in learning and memory.

Authors: D G Chain; J H Schwartz; A N Hegde
Journal: Mol Neurobiol Date: 1999 Oct-Dec Impact factor: 5.590

3. Ubiquitin-specific protease 4 mitigates Toll-like/interleukin-1 receptor signaling and regulates innate immune activation.

Authors: FangFang Zhou; Xiaofei Zhang; Hans van Dam; Peter Ten Dijke; Huizhe Huang; Long Zhang
Journal: J Biol Chem Date: 2012-01-19 Impact factor: 5.157

4. Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest.

Authors: M Di Fruscio; H Weiher; B C Vanderhyden; T Imai; T Shiomi; T A Hori; R Jaenisch; D A Gray
Journal: Mol Cell Biol Date: 1997-07 Impact factor: 4.272

5. Cell regulation, cancer and connections.

Authors: A Robinson
Journal: CMAJ Date: 1994-10-15 Impact factor: 8.262

6. A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation.

Authors: L Q Liu; R Ilaria; P D Kingsley; A Iwama; R A van Etten; J Palis; D E Zhang
Journal: Mol Cell Biol Date: 1999-04 Impact factor: 4.272

The Unp proto-oncogene encodes a nuclear protein.

1. Tissue-specificity, functional characterization and subcellular localization of a rat ubiquitin-specific processing protease, UBP109, whose mRNA expression is developmentally regulated.

Review 2. Ubiquitin-mediated proteolysis in learning and memory.

3. Ubiquitin-specific protease 4 mitigates Toll-like/interleukin-1 receptor signaling and regulates innate immune activation.

4. Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest.

5. Cell regulation, cancer and connections.

6. A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation.

7. PGP9.5 as a candidate tumor marker for non-small-cell lung cancer.

8. UBPY: a growth-regulated human ubiquitin isopeptidase.

9. Alternate exon insertion controls selective ubiquitination and degradation of different AUF1 protein isoforms.

10. The ubiquitin specific protease 4 (USP4) is a new player in the Wnt signalling pathway.