Literature DB >> 8182649

Acquired factor VIII inhibitor associated with chronic interferon-alpha therapy.

R B Stricker1, B Barlogie, D D Kiprov.   

Abstract

Therapeutic use of interferon-alpha (IFN-alpha) has been associated with the development of a variety of autoimmune disorders. We describe a patient who received chronic treatment with IFN-alpha following autologous bone marrow transplantation for multiple myeloma. The patient developed an antibody inhibitor directed against factor VIII coagulant protein (FVIIIC) leading to a fatal hemorrhagic diathesis. The association between IFN-alpha therapy and autoimmune complications deserves wider recognition and further study.

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Year:  1994        PMID: 8182649

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  9 in total

Review 1.  Tolerability of treatments for viral hepatitis.

Authors:  A Gervais; N Boyer; P Marcellin
Journal:  Drug Saf       Date:  2001       Impact factor: 5.606

Review 2.  Drug-induced lupus anticoagulants and antiphospholipid antibodies.

Authors:  Jeffrey S Dlott; Robert A S Roubey
Journal:  Curr Rheumatol Rep       Date:  2012-02       Impact factor: 4.592

3.  Is the periodic repetition of a coagulation check necessary during anti-hepatitis C virus therapy?

Authors:  F Capra; N Nicolini; M Franchini
Journal:  Gut       Date:  2006-06       Impact factor: 23.059

Review 4.  Cytokine-induced autoimmune disorders.

Authors:  P Miossec
Journal:  Drug Saf       Date:  1997-08       Impact factor: 5.606

Review 5.  [Interferon therapy and autoimmunity].

Authors:  J Fritzsch; J Krug; H J Heberling
Journal:  Med Klin (Munich)       Date:  1997-05-15

Review 6.  Rituximab and intravenous immunoglobulin (IVIG) for the management of acquired factor VIII inhibitor in multiple myeloma: case report and review of literature.

Authors:  Jameel Muzaffar; Lakshmikanth Katragadda; Sajjad Haider; Ali Javed; Elias Anaissie; Saad Usmani
Journal:  Int J Hematol       Date:  2011-12-15       Impact factor: 2.490

7.  Hepatitis C treatment with triple therapy in a patient with hemophilia A.

Authors:  Gurshawn Singh; Reuben Sass; Rayan Alamiry; Nizar Zein; Naim Alkhouri
Journal:  World J Clin Cases       Date:  2013-06-16       Impact factor: 1.337

8.  Multiple myeloma presenting with acquired factor VIII inhibitor.

Authors:  Ismail Sari; Mehmet Ali Erkurt; Ahmet Ifran; Kursat Kaptan; Cengiz Beyan
Journal:  Int J Hematol       Date:  2009-06-24       Impact factor: 2.490

Review 9.  Acquired hemophilia A and plasma cell neoplasms: a case report and review of the literature.

Authors:  Katarzyna A Jalowiec; Martin Andres; Behrouz Mansouri Taleghani; Albulena Musa; Martina Dickenmann; Anne Angelillo-Scherrer; Alicia Rovó; Johanna A Kremer Hovinga
Journal:  J Med Case Rep       Date:  2020-10-30
  9 in total

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