| Literature DB >> 8182344 |
J W Armstrong1, S J Simske, A A Beharka, S Balch, M W Luttges, S K Chapes.
Abstract
Class I and class II major histocompatibility complex (MHC) molecules play significant roles in T cell development and immune function. We show that MHCI- and MHCII-deficient mice have low numbers of macrophage precursors and circulating monocytes, as well as abnormal bone marrow cell colony-stimulating factor type 1 secretion and bone composition. We suggest that MHCI and MHCII molecules play a significant role in macrophage development.Entities:
Keywords: NASA Discipline Cell Biology; Non-NASA Center
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Year: 1994 PMID： 8182344 DOI： 10.1002/jlb.55.5.658
Source DB: PubMed Journal: J Leukoc Biol ISSN： 0741-5400 Impact factor: 4.962