Literature DB >> 8181540

Nicotine's opioid and anti-opioid interactions: proposed role in smoking behavior.

M D Aceto1, S M Scates, Z Ji, E R Bowman.   

Abstract

Nicotine produced antinociception in mice which was antagonized noncompetitively by naloxone. In addition, at significantly lower doses, nicotine noncompetitively antagonized morphine-induced antinociception. A speculative suggestion regarding the opiatergic and anti-opiatergic actions of nicotine is that it significantly promotes and maintains smoking behavior.

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Year:  1993        PMID: 8181540     DOI: 10.1016/0926-6917(93)90009-f

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  7 in total

1.  Stress response dysregulation and stress-induced analgesia in nicotine dependent men and women.

Authors:  Mustafa al'Absi; Motohiro Nakajima; John Grabowski
Journal:  Biol Psychol       Date:  2012-12-26       Impact factor: 3.251

2.  Effects of chronic khat use on cardiovascular, adrenocortical, and psychological responses to stress in men and women.

Authors:  Mustafa al'Absi; Najat Sayem Khalil; Molham Al Habori; Richard Hoffman; Koji Fujiwara; Lorentz Wittmers
Journal:  Am J Addict       Date:  2013-02-01

3.  Association of smoking with μ-opioid receptor availability before and during naltrexone blockade in alcohol-dependent subjects.

Authors:  Elise M Weerts; Gary S Wand; Hiroto Kuwabara; Xiaoqiang Xu; J James Frost; Dean F Wong; Mary E McCaul
Journal:  Addict Biol       Date:  2012-12-18       Impact factor: 4.280

4.  Acute HPA axis response to naltrexone differs in female vs. male smokers.

Authors:  Daniel J O Roche; Emma Childs; Alyssa M Epstein; Andrea C King
Journal:  Psychoneuroendocrinology       Date:  2009-10-17       Impact factor: 4.905

Review 5.  Tobacco/nicotine and endogenous brain opioids.

Authors:  Yue Xue; Edward F Domino
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2007-12-23       Impact factor: 5.067

6.  Blunted opiate modulation of hypothalamic-pituitary-adrenocortical activity in men and women who smoke.

Authors:  Mustafa al'Absi; Lorentz E Wittmers; Dorothy Hatsukami; Ruth Westra
Journal:  Psychosom Med       Date:  2008-09-16       Impact factor: 4.312

Review 7.  Endogenous opiates: 1993.

Authors:  G A Olson; R D Olson; A J Kastin
Journal:  Peptides       Date:  1994       Impact factor: 3.750

  7 in total

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