Literature DB >> 8180778

Age-related distribution of endocrine cells in the human prostate: a quantitative study.

S Battaglia1, A M Casali, A R Botticelli.   

Abstract

A morphometric analysis was performed to obtain quantitative data on age-related changes in prostatic endocrine cell (PrEC) density. Sixty prostates from subjects aged 14-74 years were studied with a semi-automatic image analysis system (ASM 68K, Leitz) applied to sections immunostained for chromogranin A-reactive cells. The highest density of PrECs (0.366 cells/mm of epithelial length) was found in the 25-54 year age group, which was significantly different from that found in prostates of the younger (0.311 cells/mm) and the older (0.261 cells/mm) age groups. The data probably reflect the higher incidence of incompletely developed glandular units in the younger group and the formation of new alveoli related to the usual glandular hyperplasia that occurs with increasing age in the older group.

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Year:  1994        PMID： 8180778     DOI： 10.1007/bf00193496

Source DB:  PubMed          Journal:  Virchows Arch        ISSN： 0945-6317            Impact factor:   4.064


  10 in total

1.  The course of neuroendocrine differentiation in prostatic carcinomas. An immunohistochemical study testing chromogranin A as an "endocrine marker".

Authors:  P A Abrahamsson; S Falkmer; K Fält; L Grimelius
Journal:  Pathol Res Pract       Date:  1989-09       Impact factor: 3.250

2.  Human prostatic endocrine-paracrine (APUD) cells. Distributional analysis with a comparison of serotonin and neuron-specific enolase immunoreactivity and silver stains.

Authors:  P A di Sant'Agnese; K L de Mesy Jensen; C J Churukian; M M Agarwal
Journal:  Arch Pathol Lab Med       Date:  1985-07       Impact factor: 5.534

3.  Neuroendocrine differentiation in prostatic carcinoma.

Authors:  P A di Sant'Agnese; K L de Mesy Jensen
Journal:  Hum Pathol       Date:  1987-08       Impact factor: 3.466

Review 4.  Neuroendocrine differentiation in carcinoma of the prostate. Diagnostic, prognostic, and therapeutic implications.

Authors:  P A di Sant'Agnese
Journal:  Cancer       Date:  1992-07-01       Impact factor: 6.860

5.  The endocrine component of prostatic carcinomas, mixed adenocarcinoma-carcinoid tumours and non-tumour prostate. Histochemical and ultrastructural identification of the endocrine cells.

Authors:  C Capella; L Usellini; R Buffa; B Frigerio; E Solcia
Journal:  Histopathology       Date:  1981-03       Impact factor: 5.087

6.  G-cell populations in resected stomachs from gastric and duodenal ulcer patients.

Authors:  T Takahashi; H Shimazu; T Yamagishi; M Tani
Journal:  Gastroenterology       Date:  1980-03       Impact factor: 22.682

7.  Enterochromaffin-like cell populations in human fundic mucosa: quantitative studies of their variations with age, sex, and plasma gastrin levels.

Authors:  D M Green; A E Bishop; G Rindi; F I Lee; M J Daly; J Domin; S R Bloom; J M Polak
Journal:  J Pathol       Date:  1989-03       Impact factor: 7.996

8.  The topographical and age distributions of neuroendocrine cells in the normal human appendix.

Authors:  P A Shaw
Journal:  J Pathol       Date:  1991-07       Impact factor: 7.996

9.  Small cell anaplastic carcinoma of the prostate: a clinical, pathological and immunohistological study of 27 patients.

Authors:  J E Oesterling; C G Hauzeur; G M Farrow
Journal:  J Urol       Date:  1992-03       Impact factor: 7.450

10.  Age-related changes in the neuroendocrine (endocrine-paracrine) cell population and the serotonin content of the guinea pig prostate.

Authors:  P A Di Sant'Agnese; N S Davis; M Chen; K L de Mesy Jensen
Journal:  Lab Invest       Date:  1987-12       Impact factor: 5.662
  10 in total

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