Literature DB >> 8180541

Management of variceal haemorrhage.

S G Williams1, D Westaby.   

Abstract

Fig 2 gives an algorithm for the treatment of bleeding oesophageal varices. Initial resuscitation of the patient is of paramount importance, ideally followed by early interventional endoscopy. Recent advances in available endoscopic techniques enable the endoscopist to suit the therapeutic approach to the clinical situation. Injection sclerotherapy remains the initial treatment of choice in bleeding patients. Endoscopic banding ligation is an alternative, best used in patients who have spontaneously stopped bleeding or as a complementary treatment a few days after the initial session of injection sclerotherapy. The tissue adhesives and thrombin can be used to treat bleeding gastric varices. [table: see text] Should the endoscopic expertise not be available, drug treatment (with somatostatin or octreotide) or balloon tamponade are the treatments of choice. Transjugular intrahepatic portal-systemic stent shunt is a new effective technique, not yet widely available, which has a documented complication rate that has yet to be fully defined. It is a good alternative to surgery as a "rescue" procedure for patients who continue to bleed despite two sessions of endoscopic intervention.

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Year:  1994        PMID: 8180541      PMCID: PMC2540071          DOI: 10.1136/bmj.308.6938.1213

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  22 in total

Review 1.  Liver transplantation in the management of bleeding oesophageal varices.

Authors:  S Iwatsuki; T E Starzl
Journal:  Baillieres Clin Gastroenterol       Date:  1992-09

Review 2.  The role of endoscopic sclerotherapy in the management of esophageal varices.

Authors:  F Hasan; B A Levine
Journal:  Dig Dis       Date:  1992       Impact factor: 2.404

Review 3.  Controversies in the management of bleeding esophageal varices (1)

Authors:  J Terblanche; A K Burroughs; K E Hobbs
Journal:  N Engl J Med       Date:  1989-05-25       Impact factor: 91.245

4.  Endoscopic sclerotherapy as compared with endoscopic ligation for bleeding esophageal varices.

Authors:  G V Stiegmann; J S Goff; P A Michaletz-Onody; J Korula; D Lieberman; Z A Saeed; R M Reveille; J H Sun; S R Lowenstein
Journal:  N Engl J Med       Date:  1992-06-04       Impact factor: 91.245

5.  Sucralfate for the prevention of early rebleeding following injection sclerotherapy for esophageal varices.

Authors:  R J Polson; D Westaby; A E Gimson; P C Hayes; A J Stellon; K Hayllar; R Williams
Journal:  Hepatology       Date:  1989-09       Impact factor: 17.425

6.  A study of octreotide in oesophageal varices.

Authors:  R McKee
Journal:  Digestion       Date:  1990       Impact factor: 3.216

7.  Successful endoscopic obturation of gastric varices with butyl cyanoacrylate.

Authors:  M J Ramond; D Valla; J F Mosnier; C Degott; J Bernuau; B Rueff; J P Benhamou
Journal:  Hepatology       Date:  1989-10       Impact factor: 17.425

8.  Octreotide infusion or emergency sclerotherapy for variceal haemorrhage.

Authors:  J J Sung; S C Chung; C W Lai; F K Chan; J W Leung; M Y Yung; C Kassianides; A K Li
Journal:  Lancet       Date:  1993-09-11       Impact factor: 79.321

9.  A comparison between emergency and delayed endoscopic injection sclerotherapy of bleeding esophageal varices in nonalcoholic portal hypertension.

Authors:  E Shemesh; A Czerniak; E Klein; A Pines; L Bat
Journal:  J Clin Gastroenterol       Date:  1990-02       Impact factor: 3.062

Review 10.  Medical management of bleeding esophageal varices.

Authors:  A K Burroughs
Journal:  Dig Dis       Date:  1992       Impact factor: 2.404

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  7 in total

Review 1.  Liver transplantation for hepatic cirrhosis in cystic fibrosis.

Authors:  G Noble-Jamieson; N Barnes; N Jamieson; P Friend; R Calne
Journal:  J R Soc Med       Date:  1996       Impact factor: 5.344

2.  Role of emergency transjugular intrahepatic portosystemic shunts.

Authors:  Jorge E Lopera
Journal:  Semin Intervent Radiol       Date:  2005-12       Impact factor: 1.513

Review 3.  Somatostatin analogues for acute bleeding oesophageal varices.

Authors:  Peter C Gøtzsche; Asbjørn Hróbjartsson
Journal:  Cochrane Database Syst Rev       Date:  2008-07-16

4.  The role of the transjugular intrahepatic portosystemic stent shunt (TIPSS) in the management of bleeding gastric varices: clinical and haemodynamic correlations.

Authors:  D Tripathi; G Therapondos; E Jackson; D N Redhead; P C Hayes
Journal:  Gut       Date:  2002-08       Impact factor: 23.059

5.  Somatostatin v placebo in bleeding oesophageal varices: randomised trial and meta-analysis.

Authors:  P C Gøtzsche; I Gjørup; H Bonnén; N E Brahe; U Becker; F Burcharth
Journal:  BMJ       Date:  1995-06-10

6.  Endoscopy management algorithms: role of cyanoacrylate glue injection and self-expanding metal stents in acute variceal haemorrhage.

Authors:  G El Sayed; S Tarff; J O'Beirne; G Wright
Journal:  Frontline Gastroenterol       Date:  2014-06-23

7.  Transesplenic access in the treatment of varicose gastrointestinal bleeding. Case and technical report.

Authors:  Rafael Birelo Martins; Priscila Mina Falsarella; Joaquim Maurício da Motta-Leal-Filho; Francisco Leonardo Galastri; Breno Boueri Affonso; Rodrigo Gobbo Garcia; Felipe Nasser
Journal:  Einstein (Sao Paulo)       Date:  2020-01-27
  7 in total

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