| Literature DB >> 8180135 |
V Ollendorff1, T Noguchi, O deLapeyriere, D Birnbaum.
Abstract
We have characterized a new human gene, named GARP, localized in the 11q14 chromosomal region. GARP comprises two coding exons, is expressed as two major transcripts of 4.4 and 2.8 kilobases, respectively, and encodes a putative transmembrane protein of 662 amino acids, the extracellular portion of which is almost entirely made of leucine-rich repeats. The molecular weight of the protein immunoprecipitated from transfected cells is 80,000. The GARP protein has structural similarities with the human GP Ib alpha and GP V platelet proteins, and with the Chaoptin, Toll, and Connectin adhesion molecules of Drosophila.Entities:
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Year: 1994 PMID： 8180135
Source DB: PubMed Journal: Cell Growth Differ ISSN： 1044-9523