Literature DB >> 8178155

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor.

K H Grabstein1, J Eisenman, K Shanebeck, C Rauch, S Srinivasan, V Fung, C Beers, J Richardson, M A Schoenborn, M Ahdieh.   

Abstract

A cytokine was identified that stimulated the proliferation of T lymphocytes, and a complementary DNA clone encoding this new T cell growth factor was isolated. The cytokine, designated interleukin-15 (IL-15), is produced by a wide variety of cells and tissues and shares many biological properties with IL-2. Monoclonal antibodies to the beta chain of the IL-2 receptor inhibited the biological activity of IL-15, and IL-15 competed for binding with IL-2, indicating that IL-15 uses components of the IL-2 receptor.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 8178155     DOI： 10.1126/science.8178155

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  370 in total

Review 1.  Cytokines in asthma.

Authors:  K F Chung; P J Barnes
Journal:  Thorax       Date:  1999-09       Impact factor: 9.139

2.  Association of B7-1 co-stimulation with the development of graft arterial disease. Studies using mice lacking B7-1, B7-2, or B7-1/B7-2.

Authors:  Y Furukawa; D A Mandelbrot; P Libby; A H Sharpe; R N Mitchell
Journal:  Am J Pathol       Date:  2000-08       Impact factor: 4.307

3.  IL-15-induced conversion of monocytes to mature dendritic cells.

Authors:  K U Saikh; A S Khan; T Kissner; R G Ulrich
Journal:  Clin Exp Immunol       Date:  2001-12       Impact factor: 4.330

4.  Production and distribution of interleukin 15 and its receptors (IL-15Ralpha and IL-R2beta) in the implant interface tissues obtained during revision of failed total joint replacement.

Authors:  S Saeed; P A Revell
Journal:  Int J Exp Pathol       Date:  2001-06       Impact factor: 1.925

5.  Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity.

Authors:  SangKon Oh; Jay A Berzofsky; Donald S Burke; Thomas A Waldmann; Liyanage P Perera
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-07       Impact factor: 11.205

6.  IL-15R alpha expression on CD8+ T cells is dispensable for T cell memory.

Authors:  Patrick R Burkett; Rima Koka; Marcia Chien; Sophia Chai; Faye Chan; Averil Ma; David L Boone
Journal:  Proc Natl Acad Sci U S A       Date:  2003-04-01       Impact factor: 11.205

7.  Induction of IL-15 by TCR/CD3 aggregation depends on IFN-gamma and protects against apoptosis of immature thymocytes in vivo.

Authors:  P Matthys; H Dooms; P Rottiers; T Mitera; L Overgergh; G Leclercq; A Billiau; J Grooten
Journal:  Clin Exp Immunol       Date:  2002-12       Impact factor: 4.330

8.  Clinical manufacturing of recombinant human interleukin 15. I. Production cell line development and protein expression in E. coli with stop codon optimization.

Authors:  Vinay V Vyas; Dominic Esposito; Terry L Sumpter; Trevor L Broadt; James Hartley; George C Knapp; Wei Cheng; Man-Shiow Jiang; John M Roach; Xiaoyi Yang; Steven L Giardina; George Mitra; Jason L Yovandich; Stephen P Creekmore; Thomas A Waldmann; Jianwei Zhu
Journal:  Biotechnol Prog       Date:  2011-12-09

9.  Effect of IL-15 and natural killer cells on osteoclasts and osteoblasts in a mouse coculture.

Authors:  Hiroaki Takeda; Takeshi Kikuchi; Kyoko Soboku; Iichiro Okabe; Hiroki Mizutani; Akio Mitani; Yuichi Ishihara; Toshihide Noguchi
Journal:  Inflammation       Date:  2014-06       Impact factor: 4.092

Review 10.  Pro- and anti-inflammatory cytokines in cutaneous leishmaniasis: a review.

Authors:  Nahid Maspi; Amir Abdoli; Fathemeh Ghaffarifar
Journal:  Pathog Glob Health       Date:  2016-09-23       Impact factor: 2.894
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.