Literature DB >> 8178152

Sex determination and dosage compensation: lessons from flies and worms.

S M Parkhurst1, P M Meneely.   

Abstract

In both Drosophila melanogaster and Caenorhabditis elegans somatic sex determination, germline sex determination, and dosage compensation are controlled by means of a chromosomal signal known as the X:A ratio. A variety of mechanisms are used for establishing and implementing the chromosomal signal, and these do not appear to be similar in the two species. Instead, the study of sex determination and dosage compensation is providing more general lessons about different types of signaling pathways used to control alternative developmental states of cells and organisms.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 8178152     DOI： 10.1126/science.8178152

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  27 in total

Review 1.  Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms.

Authors:  M E Massari; C Murre
Journal:  Mol Cell Biol       Date:  2000-01       Impact factor: 4.272

2.  Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1alpha.

Authors:  Christina M Hull; Robert C Davidson; Joseph Heitman
Journal:  Genes Dev       Date:  2002-12-01       Impact factor: 11.361

3.  The transformer2 gene in Musca domestica is required for selecting and maintaining the female pathway of development.

Authors:  Géza Burghardt; Monika Hediger; Christina Siegenthaler; Martin Moser; Andreas Dübendorfer; Daniel Bopp
Journal:  Dev Genes Evol       Date:  2005-01-21       Impact factor: 0.900

4.  Drosophila CK2 phosphorylates Deadpan, a member of the HES family of basic-helix-loop-helix (bHLH) repressors.

Authors:  Umesh C Karandikar; Jonathan Shaffer; Clifton P Bishop; Ashok P Bidwai
Journal:  Mol Cell Biochem       Date:  2005-06       Impact factor: 3.396

5.  A change of ploidy can modify epigenetic silencing.

Authors:  O Mittelsten Scheid; L Jakovleva; K Afsar; J Maluszynska; J Paszkowski
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-09       Impact factor: 11.205

6.  Activities of the Sex-lethal protein in RNA binding and protein:protein interactions.

Authors:  M Samuels; G Deshpande; P Schedl
Journal:  Nucleic Acids Res       Date:  1998-06-01       Impact factor: 16.971

7.  Unusually high recombination rate detected in the sex locus region of the honey bee (Apis mellifera).

Authors:  M Beye; G J Hunt; R E Page; M K Fondrk; L Grohmann; R F Moritz
Journal:  Genetics       Date:  1999-12       Impact factor: 4.562

Review 8.  The molecular genetics of human sex determination.

Authors:  U Wolf
Journal:  J Mol Med (Berl)       Date:  1995-07       Impact factor: 4.599

9.  B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.

Authors:  Y Zhuang; P Cheng; H Weintraub
Journal:  Mol Cell Biol       Date:  1996-06       Impact factor: 4.272

10.  Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed.

Authors:  G Jiménez; Z Paroush; D Ish-Horowicz
Journal:  Genes Dev       Date:  1997-11-15       Impact factor: 11.361
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.