Literature DB >> 817632

Carbohydrate analysis of concanavalin A-reactive and concanavalin A-nonreactive mycobacterial polysaccharides.

T M Daniel, A Misaki.   

Abstract

Concanavalin A-nonreactive polysaccharide and 2 concanavalin A-reactive polysaccharides of differing concanavalin A affinities that had been purified from culture filtrates of Mycobacterium tuberculosis were subjected to carbohydrate analysis by gas and gas-liquid chromatography. Concanavalin A-nonreactive polysaccharide was found to be D-arabinogalactan, and the concanavalin A-reactive polysaccharide of highest affinity was found to be D-arabinomannan. The lower affinity concanavalin A-reactive polysaccharide was rich in arabinose and probably represented a mixture, with more than one polysaccharide present. Glucan was found to be a significant contaminant of all 3 polysaccharides.

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Year:  1976        PMID： 817632     DOI： 10.1164/arrd.1976.113.5.705

Source DB:  PubMed          Journal:  Am Rev Respir Dis        ISSN： 0003-0805


  7 in total

1.  Immunosuppression by mycobacterial arabinomannan.

Authors:  J J Ellner; T M Daniel
Journal:  Clin Exp Immunol       Date:  1979-02       Impact factor: 4.330

2.  Demonstration of a shared epitope among mycobacterial antigens using a monoclonal antibody.

Authors:  T M Daniel; G R Olds
Journal:  Clin Exp Immunol       Date:  1985-05       Impact factor: 4.330

Review 3.  Mycobacterial antigens: a review of their isolation, chemistry, and immunological properties.

Authors:  T M Daniel; B W Janicki
Journal:  Microbiol Rev       Date:  1978-03

4.  Specificity of Mycobacterium tuberculosis antigen 5 determined with mouse monoclonal antibodies.

Authors:  T M Daniel; N J Gonchoroff; J A Katzmann; G R Olds
Journal:  Infect Immun       Date:  1984-07       Impact factor: 3.441

5.  Suppression of lymphocyte responses by tuberculous plasma and mycobacterial arabinogalactan. Monocyte dependence and indomethacin reversibility.

Authors:  M E Kleinhenz; J J Ellner; P J Spagnuolo; T M Daniel
Journal:  J Clin Invest       Date:  1981-07       Impact factor: 14.808

6.  Lipoarabinomannan and lipid-free arabinomannan antigens of Mycobacterium paratuberculosis.

Authors:  E A Sugden; B S Samagh; D R Bundle; J R Duncan
Journal:  Infect Immun       Date:  1987-03       Impact factor: 3.441

7.  Isolation and partial characterization of glycolipid fractions from Mycobacterium avium serovar 2 (Mycobacterium paratuberculosis 18) that inhibit activated macrophages.

Authors:  M E Hines; J M Jaynes; S A Barker; J C Newton; F M Enright; T G Snider
Journal:  Infect Immun       Date:  1993-01       Impact factor: 3.441
  7 in total

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