Literature DB >> 817299

Conditioned approach: an analogue of conditioned avoidance; effects of chlorpromazine and diazepam.

B Migler.   

Abstract

An analogue of the conditioned avoidance test, the conditioned approach test, was designed in which the reinforcing event was eating food rather than avoiding or escaping shock. A response to the approach stimulus resulted in immediate delivery of food. Failure to respond to the approach stimulus for 15 sec resulted in the delivery of a food pellet. Administration of chlorpormazine at 2--4 mg/kg, PO to squirrel monkeys resulted in the failure of the monkeys to respond to many approach stimuli although they promptly responded to the freely delivered food pellet. Diazepam was without effect at doses up to 100 mg/kg, PO.

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Year:  1975        PMID: 817299     DOI: 10.1016/0091-3057(75)90002-7

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN: 0091-3057            Impact factor:   3.533


  3 in total

1.  Response decrement patterns after neuroleptic and non-neuroleptic drugs.

Authors:  D J Sanger
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

2.  Stimulus efficacy, chlorpromazine, and schizophrenia.

Authors:  D E Clody; P L Carlton
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

3.  Anticipation: An Essential Feature of Anhedonia.

Authors:  Anthony G Phillips; Soyon Ahn
Journal:  Curr Top Behav Neurosci       Date:  2022
  3 in total

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