Literature DB >> 8172644

Complement factor H and related proteins: an expanding family of complement-regulatory proteins?

P F Zipfel1, C Skerka.   

Abstract

Recently, several factor-H-related molecules have been identified in humans and mice, initiating new interest in this group of serum proteins. Although no complement-regulatory activity has been demonstrated yet for the human factor-H-related proteins, the immunological and structural similarities to factor H suggest overlapping functions. Here, Peter Zipfel and Christine Skerka review these similarities and suggest a new nomenclature to identify members of the factor-H-related family.

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Year:  1994        PMID： 8172644     DOI： 10.1016/0167-5699(94)90155-4

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  33 in total

1.  Different regulation of factor H and FHL-1/reconectin by inflammatory mediators and expression of the two proteins in rheumatoid arthritis (RA).

Authors:  M A Friese; J Hellwage; T S Jokiranta; S Meri; H J Müller-Quernheim; H H Peter; H Eibel; P F Zipfel
Journal:  Clin Exp Immunol       Date:  2000-08       Impact factor: 4.330

Review 2.  CFHR Gene Variations Provide Insights in the Pathogenesis of the Kidney Diseases Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy.

Authors:  Peter F Zipfel; Thorsten Wiech; Emma D Stea; Christine Skerka
Journal:  J Am Soc Nephrol       Date:  2020-01-24       Impact factor: 10.121

3.  The C-terminus of factor H: monoclonal antibodies inhibit heparin binding and identify epitopes common to factor H and factor H-related proteins.

Authors:  W M Prodinger; J Hellwage; M Spruth; M P Dierich; P F Zipfel
Journal:  Biochem J       Date:  1998-04-01       Impact factor: 3.857

4.  Identification of human complement factor H as a chemotactic protein for monocytes.

Authors:  K Nabil; B Rihn; M C Jaurand; J M Vignaud; J Ripoche; Y Martinet; N Martinet
Journal:  Biochem J       Date:  1997-09-01       Impact factor: 3.857

5.  The human complement regulatory factor-H-like protein 1, which represents a truncated form of factor H, displays cell-attachment activity.

Authors:  J Hellwage; S Kühn; P F Zipfel
Journal:  Biochem J       Date:  1997-09-01       Impact factor: 3.857

Review 6.  The properdin pathway: an "alternative activation pathway" or a "critical amplification loop" for C3 and C5 activation?

Authors:  Richard A Harrison
Journal:  Semin Immunopathol       Date:  2017-11-22       Impact factor: 9.623

7.  Determination of complement factor H functional polymorphisms (V62I, Y402H, and E936D) using sequence-specific primer PCR and restriction fragment length polymorphisms.

Authors:  Adrienn Bíró; Zoltán Prohászka; George Füst; Bernadett Blaskó
Journal:  Mol Diagn Ther       Date:  2006       Impact factor: 4.074

8.  Identification of three physically and functionally distinct binding sites for C3b in human complement factor H by deletion mutagenesis.

Authors:  A K Sharma; M K Pangburn
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-01       Impact factor: 11.205

9.  Pro-inflammatory cytokines from Kupffer cells downregulate hepatocyte expression of adrenomedullin binding protein-1.

Authors:  Asha Jacob; Mian Zhou; Rongqian Wu; Vivienne J Halpern; Thanjavur S Ravikumar; Ping Wang
Journal:  Biochim Biophys Acta       Date:  2007-04-06

10.  Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunity.

Authors:  Sonja Grosskinsky; Melanie Schott; Christiane Brenner; Sally J Cutler; Peter Kraiczy; Peter F Zipfel; Markus M Simon; Reinhard Wallich
Journal:  PLoS One       Date:  2009-03-24       Impact factor: 3.240
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