Literature DB >> 8172643

Prevention of diabetes in the NOD mouse: implications for therapeutic intervention in human disease.

M A Bowman1, E H Leiter, M A Atkinson.   

Abstract

The prevention of insulin-dependent diabetes (IDD) in humans remains an elusive goal, despite the broad spectrum of therapeutic interventions that prevent the development of IDD in the non-obese diabetic (NOD) mouse. Can an animal model in which spontaneous autoimmune pathology is interrupted so easily serve as an archetype for the design of clinical trials aimed at the prevention of IDD in humans? In this article, Mark Bowman, Edward Leiter and Mark Atkinson review the intervention strategies that prevent IDD in the NOD mouse and indicate why these studies may well be relevant to the prevention of IDD in humans.

Entities:  

Mesh：

Year:  1994        PMID： 8172643     DOI： 10.1016/0167-5699(94)90154-6

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  13 in total

Review 1.  Preventive Treatments for Rheumatoid Arthritis: Issues Regarding Patient Preferences.

Authors:  Axel Finckh; Monica Escher; Matthew H Liang; Nick Bansback
Journal:  Curr Rheumatol Rep       Date:  2016-08       Impact factor: 4.592

2.  A simulation model for estimating direct costs of type 1 diabetes prevention.

Authors:  Jarmo Hahl; Tuula Simell; Antti Kupila; Päivi Keskinen; Mikael Knip; Jorma Ilonen; Olli Simell
Journal:  Pharmacoeconomics       Date:  2003       Impact factor: 4.981

Review 3.  The roles of the hypothalamus and the gastrointestinal tract in the prevention of inflammatory autoimmune disease.

Authors:  D Mason
Journal:  Clin Exp Immunol       Date:  1994-09       Impact factor: 4.330

4.  New seizure frequency QTL and the complex genetics of epilepsy in EL mice.

Authors:  W N Frankel; A Valenzuela; C M Lutz; E W Johnson; W F Dietrich; J M Coffin
Journal:  Mamm Genome       Date:  1995-12       Impact factor: 2.957

Review 5.  Prevention of rheumatic diseases: strategies, caveats, and future directions.

Authors:  Axel Finckh; Kevin D Deane
Journal:  Rheum Dis Clin North Am       Date:  2014-09-04       Impact factor: 2.670

6.  Down-regulation of blood-brain glucose transport in the hyperglycemic nonobese diabetic mouse.

Authors:  E M Cornford; S Hyman; M E Cornford; M Clare-Salzler
Journal:  Neurochem Res       Date:  1995-07       Impact factor: 3.996

7.  Murine autoimmune hearing loss mediated by CD4+ T cells specific for inner ear peptides.

Authors:  C Arturo Solares; Andrea E Edling; Justin M Johnson; Moo-Jin Baek; Keiko Hirose; Gordon B Hughes; Vincent K Tuohy
Journal:  J Clin Invest       Date:  2004-04       Impact factor: 14.808

8.  From non-obese diabetic to Network for the Pancreatic Organ Donor with Diabetes: New heights in type 1 diabetes research.

Authors:  Lourdes Ramirez; Abdel Rahim A Hamad
Journal:  World J Diabetes       Date:  2015-11-25

9.  Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice.

Authors:  M G von Herrath; T Dyrberg; M B Oldstone
Journal:  J Clin Invest       Date:  1996-09-15       Impact factor: 14.808

10.  Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23).

Authors:  D Daniel; D R Wegmann
Journal:  Proc Natl Acad Sci U S A       Date:  1996-01-23       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.