Stroke incidence with hypertension and ischemic heart disease in Rochester, Minnesota.

The primary contribution to increased incidence rates for ischemic stroke in Rochester, Minnesota, for the 1980 to 1984 time period in the age groups from 55 to 84 years was from those persons in the population with ischemic heart disease. The rate and pattern of the decline in incidence rates of ischemic stroke in hypertensive individuals and in nonhypertensive individuals were quite similar, showing no demonstrable population effect of antihypertensive medication. These observations emphasize that there must be some, as yet unidentified, factor that is important in the decline of stroke incidence.