| Literature DB >> 81676 |
Abstract
Cultured rat liver cells induced a strong antibody response in syngeneic rats, directed against foetal calf serum components which were incorporated into the liver cell surface from the cell-culture medium. This antibody could be removed by absorption with liver cells or glutaraldehyde-fixed foetal calf serum. It is possible that the antigenic cross-reactivity observed in earlier studies with cultured cells treated with carcinogens could be due to this foetal calf serum component.Entities:
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Year: 1978 PMID: 81676 PMCID: PMC2009748 DOI: 10.1038/bjc.1978.229
Source DB: PubMed Journal: Br J Cancer ISSN: 0007-0920 Impact factor: 7.640