Literature DB >> 8167393

On vertebral body growth.

M Doskocil1, P Valouch, V Pazderka.   

Abstract

We have studied development of vertebral bodies with special regard to the area of contact of the vertebral body with the intervertebral disc. We have investigated complete serial sections of fetuses of the 2nd to 3rd month of intrauterine life, microscopic preparations from children, adolescents and young adults. The results of our studies and deductions from our findings are as follows: 1. Cartilaginous plates on contact surfaces of vertebral bodies with intervertebral discs are genetically parts of vertebral bodies, not of the discs. 2. During ontogenesis and growth period of life typical growth (epiphyseal) cartilages with all layers described on growth cartilages of long bones are formed on the surface of these cartilaginous plates facing the vertebral bodies. 3. From the point of view of its growth, the vertebral body should be considered to be a long bone. 4. Unlike other long bones of the skeleton, vertebral body epiphyses never ossify, and after the end of the growth period of life they are reduced into thin plates of hyaline cartilage which are situated between vertebral body and intervertebral disc. 5. We assume nucleus pulposus is not a persistent residuum of notochord. 6. According to our findings the link of sacral vertebral segments is from the very beginning of development typical synchondrosis with bipolar physes without formation of primordium of intervertebral disc.

Entities:  

Mesh:

Year:  1993        PMID: 8167393

Source DB:  PubMed          Journal:  Funct Dev Morphol        ISSN: 0862-8416


  7 in total

1.  The evolutionary importance of cell ratio between notochordal and nucleus pulposus cells: an experimental 3-D co-culture study.

Authors:  Benjamin Gantenbein-Ritter; Samantha C W Chan
Journal:  Eur Spine J       Date:  2011-09-28       Impact factor: 3.134

2.  High doses of caffeine reduce in vivo osteogenic activity in prepubertal rats.

Authors:  Jiwon Shin; Yuri Choi; Jisook Kim; A-Ram Yu; Ji-Soo Shin; Yun-Young Choi; Jaesook Roh
Journal:  J Anat       Date:  2015-06-03       Impact factor: 2.610

3.  The Effects of Caffeine on the Long Bones and Testes in Immature and Young Adult Rats.

Authors:  Yoojin Kwak; Hyeonhae Choi; Jaesook Roh
Journal:  Toxicol Res       Date:  2017-04-15

4.  Effect of radioactive iodine-induced hypothyroidism on longitudinal bone growth during puberty in immature female rats.

Authors:  Hyeonhae Choi; Ki-Young Ryu; Jaesook Roh; Jaeman Bae
Journal:  Exp Anim       Date:  2018-05-22

5.  Pulsed Electromagnetic Field Stimulators Efficacy for Noninvasive Bone Growth in Spine Surgery.

Authors:  Brian Fiani; Athanasios Kondilis; Juliana Runnels; Preston Rippe; Cyrus Davati
Journal:  J Korean Neurosurg Soc       Date:  2021-06-11

Review 6.  IVD progenitor cells: a new horizon for understanding disc homeostasis and repair.

Authors:  Feng-Juan Lyu; Kenneth M Cheung; Zhaomin Zheng; Hua Wang; Daisuke Sakai; Victor Y Leung
Journal:  Nat Rev Rheumatol       Date:  2019-02       Impact factor: 20.543

7.  Activation of intervertebral disc cells by co-culture with notochordal cells, conditioned medium and hypoxia.

Authors:  Benjamin Gantenbein; Elena Calandriello; Karin Wuertz-Kozak; Lorin M Benneker; Marius J B Keel; Samantha C W Chan
Journal:  BMC Musculoskelet Disord       Date:  2014-12-11       Impact factor: 2.362

  7 in total

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