| Literature DB >> 8165232 |
G Smith1, W G McGimpsey, M C Lynch, I E Kochevar, R W Redmond.
Abstract
A novel oxygen-independent photosensitization mechanism from the upper triplet state (Tn) of rose bengal has been demonstrated by selectively populating Tn by sequential two-color laser excitation. Products formed from Tn inhibit red blood cell acetylcholinesterase and decrease viability of P388D1 mouse macrophage monocyte cells as measured by trypan blue exclusion assay. Laser flash photolysis studies indicate that Tn reacts efficiently, as evidenced by permanent photobleaching of T1 absorption, with chemical yields approaching unit efficiency. This mechanism may have application for oxygen deficient photosensitization under high intensity, pulsed laser irradiation.Entities:
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Year: 1994 PMID： 8165232 DOI： 10.1111/j.1751-1097.1994.tb05012.x
Source DB: PubMed Journal: Photochem Photobiol ISSN： 0031-8655 Impact factor: 3.421