Literature DB >> 8165176

Evaluation of retinoids as therapeutic agents in dermatology.

A H Lewin1, M E Bos, F C Zusi, X Nair, G Whiting, P Bouquin, G Tetrault, F I Carroll.   

Abstract

Evaluation of 13-cis-12-substituted analogues of retinoic acid in a series of dermatologic screens has revealed that structural modifications can lead to selectivity and specificity. An analogue, 11-cis,13-cis-12-hydroxymethylretinoic acid, delta-lactone, has been found to have good activity and to be devoid of topical and systemic toxicity.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 8165176     DOI： 10.1023/a:1018938920796

Source DB:  PubMed          Journal:  Pharm Res        ISSN： 0724-8741            Impact factor:   4.200


  9 in total

Review 1.  Polyamines in rapid growth and cancer.

Authors:  J Jänne; H Pösö; A Raina
Journal:  Biochim Biophys Acta       Date:  1978-04-06

Review 2.  Experimental animal integumental models for screening potential dermatologic drugs.

Authors:  E J Van Scott
Journal:  Adv Biol Skin       Date:  1972

3.  Therapeutic effects of an aromatic retinoic acid analog on chemically induced skin papillomas and carcinomas of mice.

Authors:  W Bollag
Journal:  Eur J Cancer       Date:  1974-11       Impact factor: 9.162

4.  The effect on rhino mouse skin of agents which influence keratinization and exfoliation.

Authors:  L H Kligman; A M Kligman
Journal:  J Invest Dermatol       Date:  1979-11       Impact factor: 8.551

5.  Vitamin A acid (retinoic acid), a potent inhibitor of 12-O-tetradecanoyl-phorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis.

Authors:  A K Verma; R K Boutwell
Journal:  Cancer Res       Date:  1977-07       Impact factor: 12.701

6.  The tumor promoter 12-O-tetradecanoylphorbol-13-acetate induces ornithine decarboxylase in proliferating basal cells but not in differentiating cells from mouse epidermis.

Authors:  U Lichti; E Patterson; H Hennings; S H Yuspa
Journal:  J Cell Physiol       Date:  1981-05       Impact factor: 6.384

Review 7.  Animal assays for anti-psoriatic, retinoid and sun protective agents.

Authors:  N J Lowe; M J Connor; R Ashton; M Wortzman
Journal:  Br J Dermatol       Date:  1984-07       Impact factor: 9.302

8.  Effect of retinoic acid pretreatment on 12-O-tetradecanoylphorbol-13-acetate-induced cell population kinetics and polyamine biosynthesis in hairless mouse epidermis.

Authors:  E G Astrup; J E Paulsen
Journal:  Carcinogenesis       Date:  1982       Impact factor: 4.944

9.  Histologic changes in the skin of the rhino mouse (hrrhhrrh) induced by retinoids.

Authors:  R E Ashton; M J Connor; N J Lowe
Journal:  J Invest Dermatol       Date:  1984-06       Impact factor: 8.551
  9 in total
  1 in total

1.  Evaluation of retinoid lactones as topical therapeutic agents in dermatology.

Authors:  A H Lewin; S L Black; M E Bos; R R Goehring; X Nair; G Whiting; P Bouquin; G Tetrault; F I Carroll
Journal:  Pharm Res       Date:  1995-07       Impact factor: 4.200
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.