Literature DB >> 8164829

Tourette's syndrome in a special education population: a pilot study involving a single school district.

R Kurlan1, D Whitmore, C Irvine, M P McDermott, P G Como.   

Abstract

To determine whether children requiring special education represent a high-risk group for identifying Tourette's syndrome (TS), we performed direct examinations for the presence of tics in 35 special education and 35 regular classroom students from a single school district. Of the special education students, nine (26%) had definite or probable tics as compared with only two (6%) of the regular classroom students. About one-third of the students with tics currently meet diagnostic criteria for TS and probably more will do so in the future. About one-half of the subjects with tics have evidence of obsessive-compulsive behavior (OCB) or an attention-deficit hyperactivity disorder (ADHD). For three randomly selected students with definite tics, direct examinations of first-degree relatives revealed the presence of tics in all families. Subjects to the limitations of this pilot study, we conclude that TS and related tic disorders are commonly associated with the need for special education in this single school district. TS might also be an important contributor to school problems in the childhood population at large and may be a highly prevalent condition. In addition, we conclude that childhood tics are associated with OCB and ADHD, are genetically determined, and are part of the TS clinical spectrum.

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Year:  1994        PMID: 8164829     DOI: 10.1212/wnl.44.4.699

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  13 in total

1.  Prevalence and clinical correlates of tic disorders in a community sample of school-age children.

Authors:  Janne Tabori Kraft; Søren Dalsgaard; Carsten Obel; Per Hove Thomsen; Tine Brink Henriksen; Lawrence Scahill
Journal:  Eur Child Adolesc Psychiatry       Date:  2011-10-27       Impact factor: 4.785

2.  Intermediate inheritance of Tourette syndrome, assuming assortative mating.

Authors:  S J Hasstedt; M Leppert; F Filloux; B J van de Wetering; W M McMahon
Journal:  Am J Hum Genet       Date:  1995-09       Impact factor: 11.025

3.  Bridging neuroscience and clinical psychology: cognitive behavioral and psychophysiological models in the evaluation and treatment of Gilles de la Tourette syndrome.

Authors:  Marc E Lavoie; Julie Leclerc; Kieron P O'Connor
Journal:  Neuropsychiatry (London)       Date:  2013-02-01

Review 4.  Gilles de la Tourette syndrome: symptomatic treatment based on evidence.

Authors:  M M Robertson; J S Stern
Journal:  Eur Child Adolesc Psychiatry       Date:  2000       Impact factor: 4.785

5.  A Brazilian cohort of patients with Tourette's syndrome.

Authors:  F Cardoso; C C Veado; J T de Oliveira
Journal:  J Neurol Neurosurg Psychiatry       Date:  1996-02       Impact factor: 10.154

Review 6.  Gilles de la Tourette's syndrome and its impact in the UK.

Authors:  J S Stern; S Burza; M M Robertson
Journal:  Postgrad Med J       Date:  2005-01       Impact factor: 2.401

7.  Prevalence of tic disorders among primary school students in the city of Pavia, Italy.

Authors:  G Lanzi; C A Zambrino; C Termine; M Palestra; O Ferrari Ginevra; S Orcesi; P Manfredi; E Beghi
Journal:  Arch Dis Child       Date:  2004-01       Impact factor: 3.791

Review 8.  Clinical course of Tourette syndrome.

Authors:  Michael H Bloch; James F Leckman
Journal:  J Psychosom Res       Date:  2009-12       Impact factor: 3.006

9.  Hispidulin alleviated methamphetamine-induced hyperlocomotion by acting at α6 subunit-containing GABAA receptors in the cerebellum.

Authors:  Yu-Hsiang Liao; Hsin-Jung Lee; Wei-Jan Huang; Pi-Chuan Fan; Lih-Chu Chiou
Journal:  Psychopharmacology (Berl)       Date:  2016-07-06       Impact factor: 4.530

10.  New therapeutic approach to Tourette Syndrome in children based on a randomized placebo-controlled double-blind phase IV study of the effectiveness and safety of magnesium and vitamin B6.

Authors:  Rafael Garcia-Lopez; Emilio Perea-Milla; Cesar Ruiz Garcia; Francisco Rivas-Ruiz; Julio Romero-Gonzalez; Jose L Moreno; Vicente Faus; Guadalupe del Castillo Aguas; Juan C Ramos Diaz
Journal:  Trials       Date:  2009-03-10       Impact factor: 2.279

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