Literature DB >> 8164823

Cognitive slowing in Parkinson's and Alzheimer's patients: distinguishing bradyphrenia from dementia.

D S Pate1, D I Margolin.   

Abstract

The contribution of cognitive slowing to the slowed performance of patients with Parkinson's disease (PD) is a matter of long-standing debate. In this study, we contrasted the performance of PD patients on two reaction-time tasks with the performance of Alzheimer's disease (AD) patients, young normal subjects, and elderly normal subjects. Both nondemented and demented PD patients showed cognitive as well as motor slowing, and the extent of cognitive slowing varied with overall cognitive status. Moreover, by comparison with the cognitive slowing in AD patients, cognitive slowing in PD patients was disproportionate to their general level of cognitive performance. We suggest that this disproportionality be used to differentiate the concepts of bradyphrenia and nonspecific cognitive slowing.

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Year:  1994        PMID: 8164823     DOI: 10.1212/wnl.44.4.669

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  10 in total

1.  Effect of interstimulus interval on visual P300 in Parkinson's disease.

Authors:  L Wang; Y Kuroiwa; T Kamitani; T Takahashi; Y Suzuki; O Hasegawa
Journal:  J Neurol Neurosurg Psychiatry       Date:  1999-10       Impact factor: 10.154

Review 2.  Sharpening the boundaries of Parkinson-associated dementia: recommendation for a neuropsychological diagnostic procedure.

Authors:  Marc R Bothe; Ingo Uttner; Markus Otto
Journal:  J Neural Transm (Vienna)       Date:  2010-01-30       Impact factor: 3.575

3.  Onset of Mild Cognitive Impairment in Parkinson Disease.

Authors:  David K Johnson; Zachary Langford; Mauricio Garnier-Villarreal; John C Morris; James E Galvin
Journal:  Alzheimer Dis Assoc Disord       Date:  2016 Apr-Jun       Impact factor: 2.703

4.  Differential effects of subthalamic nucleus stimulation in advanced Parkinson disease on reaction time performance.

Authors:  Yasin Temel; Arjan Blokland; Linda Ackermans; Peter Boon; Vivianne H J M van Kranen-Mastenbroek; E A M Beuls; Geert H Spincemaille; Veerle Visser-Vandewalle
Journal:  Exp Brain Res       Date:  2005-11-05       Impact factor: 1.972

5.  Parkinson's disease and the Stroop color word test: processing speed and interference algorithms.

Authors:  Shannon M Sisco; Elizabeth Slonena; Michael S Okun; Dawn Bowers; Catherine C Price
Journal:  Clin Neuropsychol       Date:  2016-06-06       Impact factor: 3.535

Review 6.  "Pseudo-syndromes" associated with Parkinson disease, dementia, apathy, anxiety, and depression.

Authors:  Howard D Weiss; Gregory M Pontone
Journal:  Neurol Clin Pract       Date:  2019-08

7.  Computational Modeling for Neuropsychological Assessment of Bradyphrenia in Parkinson's Disease.

Authors:  Alexander Steinke; Florian Lange; Caroline Seer; Merle K Hendel; Bruno Kopp
Journal:  J Clin Med       Date:  2020-04-18       Impact factor: 4.241

8.  Association of low-frequency and rare coding variants with information processing speed.

Authors:  Jan Bressler; Gail Davies; Albert V Smith; Yasaman Saba; Joshua C Bis; Xueqiu Jian; Caroline Hayward; Lisa Yanek; Jennifer A Smith; Saira S Mirza; Ruiqi Wang; Hieab H H Adams; Diane Becker; Eric Boerwinkle; Archie Campbell; Simon R Cox; Gudny Eiriksdottir; Chloe Fawns-Ritchie; Rebecca F Gottesman; Megan L Grove; Xiuqing Guo; Edith Hofer; Sharon L R Kardia; Maria J Knol; Marisa Koini; Oscar L Lopez; Riccardo E Marioni; Paul Nyquist; Alison Pattie; Ozren Polasek; David J Porteous; Igor Rudan; Claudia L Satizabal; Helena Schmidt; Reinhold Schmidt; Stephen Sidney; Jeannette Simino; Blair H Smith; Stephen T Turner; Sven J van der Lee; Erin B Ware; Rachel A Whitmer; Kristine Yaffe; Qiong Yang; Wei Zhao; Vilmundur Gudnason; Lenore J Launer; Annette L Fitzpatrick; Bruce M Psaty; Myriam Fornage; M Arfan Ikram; Cornelia M van Duijn; Sudha Seshadri; Thomas H Mosley; Ian J Deary
Journal:  Transl Psychiatry       Date:  2021-12-04       Impact factor: 6.222

9.  A Common Function of Basal Ganglia-Cortical Circuits Subserving Speed in Both Motor and Cognitive Domains.

Authors:  Takashi Hanakawa; Andrew M Goldfine; Mark Hallett
Journal:  eNeuro       Date:  2017-12-08

10.  An Investigation of Limbs Exercise as a Treatment in Improving the Psychomotor Speed in Older Adults with Mild Cognitive Impairment.

Authors:  Hao Jiang; Shihui Chen; Lina Wang; Xiaolei Liu
Journal:  Brain Sci       Date:  2019-10-16
  10 in total

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