| Literature DB >> 8164822 |
P Montagna1, P Cortelli, L Monari, G Pierangeli, P Parchi, R Lodi, S Iotti, C Frassineti, P Zaniol, E Lugaresi.
Abstract
We investigated 22 patients with migraine without aura, all drug-free and in headache-free periods, by means of 31P-magnetic resonance spectroscopy (MRS) of brain and muscle. Brain 31P-MRS showed significantly low phosphocreatine, increased adenosine diphosphate, and decreased phosphorylation potential. There was a slow rate of phosphocreatine recovery after exercise in the muscle of 12 of 22 patients. Energy metabolism is abnormal in migraine without aura, as previously demonstrated in patients with migraine stroke and migraine with aura.Entities:
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Year: 1994 PMID: 8164822 DOI: 10.1212/wnl.44.4.666
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910