Literature DB >> 8164225

Exaggerated fibrosis in patients with systemic sclerosis (scleroderma) following radiation therapy.

M Abu-Shakra1, P Lee.   

Abstract

We describe 2 patients with systemic sclerosis (scleroderma) who developed severe localized skin thickening following radiation therapy for cancer. Radiation therapy may result in intense localized areas of fibrosis in patients with scleroderma. The fibrosis may extend beyond the irradiation portals and result in damage to underlying viscera. Radiotherapy may precipitate scleroderma or cause a generalized worsening of the underlying disease.

Entities:  

Mesh：

Year:  1993        PMID： 8164225

Source DB:  PubMed          Journal:  J Rheumatol        ISSN： 0315-162X            Impact factor:   4.666


  20 in total

1.  High-dose immunosuppressive therapy for severe systemic sclerosis: initial outcomes.

Authors:  Peter A McSweeney; Richard A Nash; Keith M Sullivan; Jan Storek; Leslie J Crofford; Roger Dansey; Maureen D Mayes; Kevin T McDonagh; J Lee Nelson; Theodore A Gooley; Leona A Holmberg; C S Chen; Mark H Wener; Katherine Ryan; Julie Sunderhaus; Ken Russell; John Rambharose; Rainer Storb; Daniel E Furst
Journal:  Blood       Date:  2002-09-01       Impact factor: 22.113

2.  Close temporal relationship between onset of cancer and scleroderma in patients with RNA polymerase I/III antibodies.

Authors:  Ami A Shah; Antony Rosen; Laura Hummers; Fredrick Wigley; Livia Casciola-Rosen
Journal:  Arthritis Rheum       Date:  2010-09

Review 3.  Cancer and scleroderma: a paraneoplastic disease with implications for malignancy screening.

Authors:  Ami A Shah; Livia Casciola-Rosen
Journal:  Curr Opin Rheumatol       Date:  2015-11       Impact factor: 5.006

4.  [Acute and chronic radiation effects in patients with collagenoses].

Authors:  S Neubauer
Journal:  Strahlenther Onkol       Date:  1998-04       Impact factor: 3.621

5.  Mechanistic and clinical insights at the scleroderma-cancer interface.

Authors:  Ami A Shah; Livia Casciola-Rosen
Journal:  J Scleroderma Relat Disord       Date:  2017-10-05

6.  Associations of breast cancer development in patients with systemic sclerosis: an exploratory study.

Authors:  Chris T Derk
Journal:  Clin Rheumatol       Date:  2007-02-02       Impact factor: 2.980

7.  Renal shielding and dosimetry for patients with severe systemic sclerosis receiving immunoablation with total body irradiation in the scleroderma: cyclophosphamide or transplantation trial.

Authors:  Oana I Craciunescu; Beverly A Steffey; Chris R Kelsey; Nicole A Larrier; Cathy J Paarz-Largay; Robert G Prosnitz; Nelson Chao; John Chute; Cristina Gasparetto; Mitchell Horwitz; Gwynn Long; David Rizzieri; Keith M Sullivan
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-08-26       Impact factor: 7.038

Review 8.  Gastrointestinal radiation injury: symptoms, risk factors and mechanisms.

Authors:  Abobakr K Shadad; Frank J Sullivan; Joseph D Martin; Laurence J Egan
Journal:  World J Gastroenterol       Date:  2013-01-14       Impact factor: 5.742

Review 9.  Gastrointestinal radiation injury: prevention and treatment.

Authors:  Abobakr K Shadad; Frank J Sullivan; Joseph D Martin; Laurence J Egan
Journal:  World J Gastroenterol       Date:  2013-01-14       Impact factor: 5.742

10.  Adenosine A2A receptor plays an important role in radiation-induced dermal injury.

Authors:  Miguel Perez-Aso; Aránzazu Mediero; Yee Cheng Low; Jamie Levine; Bruce N Cronstein
Journal:  FASEB J       Date:  2015-09-28       Impact factor: 5.191
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