Differentiation of multiple giant cell lesions, Noonan-like syndrome, and (occult) hyperparathyroidism. Case report and review of the literature.

The history is reported of a boy known to have von Recklinghausen neurofibromatosis and multiple recurrent central giant cell granulomata of the mandible and maxilla. This paper discusses the problem of differentiating multiple central giant cell granulomata, Noonan-like/multiple giant cell lesion syndrome, and brown tumor resulting from (occult) hyperparathyroidism.