Literature DB >> 8163802

Repeated large-dose haptoglobin therapy in an extensively burned patient: case report.

H Imaizumi1, K Tsunoda, N Ichimiya, T Okamoto, A Namiki.   

Abstract

The case of a 24-year-old man who sustained a 100% body surface area burn and inhalation injury is presented. Hemoglobinuria reappeared 2 hours after haptoglobin was first administered. In addition to individualized fluid resuscitation and plasma administration, a large dose of haptoglobin was repeatedly administered while we monitored for occult blood in the centrifuged urine. As a result, postburn shock and acute renal failure were prevented.

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Year:  1994        PMID： 8163802     DOI： 10.1016/0736-4679(94)90009-4

Source DB:  PubMed          Journal:  J Emerg Med        ISSN： 0736-4679            Impact factor:   1.484


  6 in total

Review 1.  Cell-free hemoglobin and its scavenger proteins: new disease models leading the way to targeted therapies.

Authors:  Dominik J Schaer; Paul W Buehler
Journal:  Cold Spring Harb Perspect Med       Date:  2013-06-01       Impact factor: 6.915

Review 2.  Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins.

Authors:  Dominik J Schaer; Paul W Buehler; Abdu I Alayash; John D Belcher; Gregory M Vercellotti
Journal:  Blood       Date:  2012-12-20       Impact factor: 22.113

Review 3.  Mechanisms of haemolysis-induced kidney injury.

Authors:  Kristof Van Avondt; Erfan Nur; Sacha Zeerleder
Journal:  Nat Rev Nephrol       Date:  2019-08-27       Impact factor: 28.314

Review 4.  Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders.

Authors:  Ann Smith; Russell J McCulloh
Journal:  Front Physiol       Date:  2015-06-30       Impact factor: 4.566

Review 5.  Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development.

Authors:  Dominik J Schaer; Francesca Vinchi; Giada Ingoglia; Emanuela Tolosano; Paul W Buehler
Journal:  Front Physiol       Date:  2014-10-28       Impact factor: 4.566

6.  Undetectable haptoglobin is associated with major adverse kidney events in critically ill burn patients.

Authors:  François Dépret; Chloé Dunyach; Christian De Tymowski; Maïté Chaussard; Aurélien Bataille; Axelle Ferry; Nabila Moreno; Alexandru Cupaciu; Sabri Soussi; Mourad Benyamina; Alexandre Mebazaa; Kevin Serror; Marc Chaouat; Jean-Pierre Garnier; Romain Pirracchio; Matthieu Legrand
Journal:  Crit Care       Date:  2017-09-26       Impact factor: 9.097
  6 in total

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