| Literature DB >> 8162441 |
Abstract
Paralytic poliomyelitis is caused by the destruction of neurons in the central nervous system during the lytic replication of poliovirus. The human gene for the poliovirus receptor has been cloned recently, and transgenic mice generated that are susceptible to this virus. This has allowed the critical amino acids that determine the specificity of poliovirus to be identified.Entities:
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Year: 1994 PMID: 8162441 DOI: 10.1016/0966-842x(94)90125-2
Source DB: PubMed Journal: Trends Microbiol ISSN: 0966-842X Impact factor: 17.079