Literature DB >> 8162439

Host cell proteases controlling virus pathogenicity.

H D Klenk1, W Garten.   

Abstract

The majority of viral glycoproteins that undergo post-translational proteolysis are cleaved by ubiquitous intracellular proteases; however, a minority are cleaved by secreted proteases available only in a few host systems. The interplay of viral glycoproteins and cellular proteases may have a pivotal role in the spread of infection, host range and pathogenicity.

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Year:  1994        PMID： 8162439     DOI： 10.1016/0966-842x(94)90123-6

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  190 in total

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2.  A protein-based therapeutic for human cytomegalovirus infection.

Authors:  F Jean; L Thomas; S S Molloy; G Liu; M A Jarvis; J A Nelson; G Thomas
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3.  Role of metastability and acidic pH in membrane fusion by tick-borne encephalitis virus.

Authors:  K Stiasny; S L Allison; C W Mandl; F X Heinz
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

4.  Reverse genetics demonstrates that proteolytic processing of the Ebola virus glycoprotein is not essential for replication in cell culture.

Authors:  Gabriele Neumann; Heinz Feldmann; Shinji Watanabe; Igor Lukashevich; Yoshihiro Kawaoka
Journal:  J Virol       Date:  2002-01       Impact factor: 5.103

5.  The Lassa virus glycoprotein precursor GP-C is proteolytically processed by subtilase SKI-1/S1P.

Authors:  O Lenz; J ter Meulen; H D Klenk; N G Seidah; W Garten
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-16       Impact factor: 11.205

6.  Endoproteolytic processing of the lymphocytic choriomeningitis virus glycoprotein by the subtilase SKI-1/S1P.

Authors:  Winfried R Beyer; Dennis Pöpplau; Wolfgang Garten; Dorothee von Laer; Oliver Lenz
Journal:  J Virol       Date:  2003-03       Impact factor: 5.103

7.  Human pulmonary microvascular endothelial cells support productive replication of highly pathogenic avian influenza viruses: possible involvement in the pathogenesis of human H5N1 virus infection.

Authors:  Hui Zeng; Claudia Pappas; Jessica A Belser; Katherine V Houser; Weiming Zhong; Debra A Wadford; Troy Stevens; Ron Balczon; Jacqueline M Katz; Terrence M Tumpey
Journal:  J Virol       Date:  2011-11-09       Impact factor: 5.103

8.  Cleavage at the furin consensus sequence RAR/KR(109) and presence of the intervening peptide of the respiratory syncytial virus fusion protein are dispensable for virus replication in cell culture.

Authors:  Gert Zimmer; Karl-Klaus Conzelmann; Georg Herrler
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

9.  Cleavage of influenza a virus hemagglutinin in human respiratory epithelium is cell associated and sensitive to exogenous antiproteases.

Authors:  Oleg P Zhirnov; Mine R Ikizler; Peter F Wright
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

10.  Studies of the membrane fusion activities of fusion peptide mutants of influenza virus hemagglutinin.

Authors:  D A Steinhauer; S A Wharton; J J Skehel; D C Wiley
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103
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