Literature DB >> 8162434

The multigenic nature of RNA virus adaptation to plants.

W De Jong1, K Mise, P Ahlquist.   

Abstract

Molecular genetic studies of RNA virus host range suggest that successful systemic infection requires many or all viral genes to have some degree of specific adaptation to the host. In some cases, accommodation to the host appears to be required for viral gene products to fulfil their primary functions in viral multiplication, while in other cases, adaptation seems to be required to avoid eliciting host defenses.

Mesh:

Year:  1994        PMID: 8162434     DOI: 10.1016/0966-842x(94)90342-5

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN: 0966-842X            Impact factor:   17.079


  2 in total

1.  Helicase and capping enzyme active site mutations in brome mosaic virus protein 1a cause defects in template recruitment, negative-strand RNA synthesis, and viral RNA capping.

Authors:  T Ahola; J A den Boon; P Ahlquist
Journal:  J Virol       Date:  2000-10       Impact factor: 5.103

2.  The polymerase-like core of brome mosaic virus 2a protein, lacking a region interacting with viral 1a protein in vitro, maintains activity and 1a selectivity in RNA replication.

Authors:  E Smirnyagina; N S Lin; P Ahlquist
Journal:  J Virol       Date:  1996-07       Impact factor: 5.103

  2 in total

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