Literature DB >> 816211

Evaluating new antimalarial drugs against trophozoite induced Plasmodium cynomolgi malaria in rhesus monkeys.

D E Davidson, D O Johnsen, P Tanticharoenyos, R L Hickman, K E Kinnamon.   

Abstract

An antimalarial drug testing system is described which utilizes trophozoite induced Plasmodium cynomolgi malaria in rhesus monkeys. The schizonticidal activity of standard antimalarial drugs in this system is reported. The system accurately predicted antimalarial activity in man of 8 of 9 compounds selected for clinical trials.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 816211     DOI： 10.4269/ajtmh.1976.25.26

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  8 in total

1.  Antimalarial activity of natural and synthetic prodiginines.

Authors:  Kancharla Papireddy; Martin Smilkstein; Jane Xu Kelly; Shaimaa M Salem; Mamoun Alhamadsheh; Stuart W Haynes; Gregory L Challis; Kevin A Reynolds
Journal:  J Med Chem       Date:  2011-07-08       Impact factor: 7.446

2.  Antimalarial activities of WR-194,965, an alpha-amino-o-cresol derivative.

Authors:  L H Schmidt; R Crosby
Journal:  Antimicrob Agents Chemother       Date:  1978-11       Impact factor: 5.191

3.  New tissue schizontocidal antimalarial drugs.

Authors:  D E Davidson; A L Ager; J L Brown; F E Chapple; R E Whitmire; R N Rossan
Journal:  Bull World Health Organ       Date:  1981       Impact factor: 9.408

4.  Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta).

Authors:  Geoffrey S Dow; Montip Gettayacamin; Pranee Hansukjariya; Rawiwan Imerbsin; Srawuth Komcharoen; Jetsumon Sattabongkot; Dennis Kyle; Wilbur Milhous; Simon Cozens; David Kenworthy; Anne Miller; Jim Veazey; Colin Ohrt
Journal:  Malar J       Date:  2011-07-29       Impact factor: 2.979

5.  HIV treatments reduce malaria liver stage burden in a non-human primate model of malaria infection at clinically relevant concentrations in vivo.

Authors:  Charlotte V Hobbs; Jillian Neal; Solomon Conteh; Liam Donnelly; Jingyang Chen; Kennan Marsh; Lynn Lambert; Sachy Orr-Gonzalez; Jessica Hinderer; Sara Healy; William Borkowsky; Scott R Penzak; Sumana Chakravarty; Stephen L Hoffman; Patrick E Duffy
Journal:  PLoS One       Date:  2014-07-02       Impact factor: 3.240

6.  Neither the HIV protease inhibitor lopinavir-ritonavir nor the antimicrobial trimethoprim-sulfamethoxazole prevent malaria relapse in plasmodium cynomolgi-infected non-human primates.

Authors:  Charlotte V Hobbs; Saurabh Dixit; Scott R Penzak; Tejram Sahu; Sachy Orr-Gonzalez; Lynn Lambert; Katie Zeleski; Jingyang Chen; Jillian Neal; William Borkowsky; Yimin Wu; Patrick E Duffy
Journal:  PLoS One       Date:  2014-12-26       Impact factor: 3.240

7.  Stereospecific synthesis of 23-hydroxyundecylprodiginines and analogues and conversion to antimalarial premarineosins via a Rieske oxygenase catalyzed bicyclization.

Authors:  Papireddy Kancharla; Wanli Lu; Shaimaa M Salem; Jane Xu Kelly; Kevin A Reynolds
Journal:  J Org Chem       Date:  2014-11-18       Impact factor: 4.354

Review 8.  Prodigiosin: a promising biomolecule with many potential biomedical applications.

Authors:  German A Islan; Boris Rodenak-Kladniew; Nehuen Noacco; Nelson Duran; Guillermo R Castro
Journal:  Bioengineered       Date:  2022-06       Impact factor: 6.832
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.