Literature DB >> 8158167

New cycloartanol sulfates from the alga Tydemania expeditionis: inhibitors of the protein tyrosine kinase pp60v-src.

M Govindan1, S A Abbas, F J Schmitz, R H Lee, J S Papkoff, D L Slate.   

Abstract

Bioactivity-directed fractionation of the extracts of the green alga Tydemania expeditionis using the protein tyrosine kinase pp60v-src led to the isolation of three new cycloartanol disulfates, 1-3, which show modest inhibition of this enzyme. The structures were deduced by spectroscopic methods.

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Year:  1994        PMID： 8158167     DOI： 10.1021/np50103a010

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  6 in total

Review 1.  Survey of marine natural product structure revisions: a synergy of spectroscopy and chemical synthesis.

Authors:  Takashi L Suyama; William H Gerwick; Kerry L McPhail
Journal:  Bioorg Med Chem       Date:  2011-06-12       Impact factor: 3.641

2.  Capisterones A and B, which enhance fluconazole activity in Saccharomyces cerevisiae, from the marine green alga Penicillus capitatus.

Authors:  Xing-Cong Li; Melissa R Jacob; Yuanqing Ding; Ameeta K Agarwal; Troy J Smillie; Shabana I Khan; Dale G Nagle; Daneel Ferreira; Alice M Clark
Journal:  J Nat Prod       Date:  2006-04       Impact factor: 4.050

3.  Rapid identification of triterpenoid sulfates and hydroxy fatty acids including two new constituents from Tydemania expeditionis by liquid chromatography-mass spectrometry.

Authors:  Jian-Long Zhang; Julia Kubanek; Mark E Hay; William Aalbersberg; Wen-Cai Ye; Ren-Wang Jiang
Journal:  J Mass Spectrom       Date:  2011-09       Impact factor: 1.982

4.  Structures and absolute configurations of sulfate-conjugated triterpenoids including an antifungal chemical defense of the green macroalga Tydemania expeditionis.

Authors:  Ren-Wang Jiang; Amy L Lane; Lauren Mylacraine; Kenneth I Hardcastle; Craig R Fairchild; William Aalbersberg; Mark E Hay; Julia Kubanek
Journal:  J Nat Prod       Date:  2008-09-03       Impact factor: 4.050

Review 5.  Antitumor Profile of Carbon-Bridged Steroids (CBS) and Triterpenoids.

Authors:  Valery M Dembitsky; Tatyana A Gloriozova; Vladimir V Poroikov
Journal:  Mar Drugs       Date:  2021-06-03       Impact factor: 5.118

6.  Biological importance of marine algae.

Authors:  Ali A El Gamal
Journal:  Saudi Pharm J       Date:  2010-01       Impact factor: 4.330
  6 in total

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